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Estimation of the effectiveness of the prenatal care of an unborn child on the basis of the analysis of heart rate variability of both the mother and fetus., with the 187-channel electrocardiography

Research Project

Project/Area Number 25462573
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Obstetrics and gynecology
Research InstitutionIwate Medical University

Principal Investigator

FUKUSHIMA AKIMUNE  岩手医科大学, 医学部, 教授 (20208937)

Co-Investigator(Kenkyū-buntansha) KOBAYASHI Koichiro  岩手大学, 工学部, 教授 (60277233)
中居 賢司  岩手医科大学, 歯学部, 教授 (90146035)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords胎教 / 高分解能心電図 / RTc dispersion / NT proBNP / ANP / 母体心機能リスク / 妊婦自律神経活動 / 妊婦心機能 / 胎児自律神経活動 / 妊婦母体自律神経活動 / 高分解能心電計
Outline of Final Research Achievements

This study estimated the effectiveness of the prenatal care of an unborn child, which was impossible to scientifically analyze before the introduction of vector-projected 187-channel electrocardiography, which is an accurate and noninvasive tool . Changes in the cardiac volume and heart muscle occur in the circulatory dynamics in pregnancy. As the fetus is influenced by the mother’s situation during the gestational period, and this study particularly involved electrocardiographic analysis, a precise study of the maternal cardiac function was needed before the analysis of the fetus. Thus, we estimated the peripartum cardiac load in this study. This study may help in the prognosis and prevention of cardiomyopathy in pregnant and postpartum women by using the vector synthesis high-resolution electrocardiography and atrial Natriuretic Peptide (ANP) and N-terminal pro-brain natriuretic peptide (NT-proBNP).

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2016 2015 2013

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (3 results)

  • [Journal Article] Detection of peripartum myocardial burden by vector-projected 187 channel electrocardiography and serum NT-pro BNP2013

    • Author(s)
      Miyuki Terata, Kenji Nakai, Akimune Fukushima, Manabu Itoh, Akihiko Kikuchi, Toru Sugiyama
    • Journal Title

      Internatinal Heart Journal

      Volume: 54 Pages: 140-145

    • NAID

      130003364458

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 周産期における母体心機能の評価の重要性2013

    • Author(s)
      福島明宗
    • Journal Title

      Cadiovascular Anesthesia

      Volume: 17 Pages: 93-99

    • Related Report
      2013 Research-status Report
  • [Presentation] 高分解心電計の二次減分布図に依る妊産褥婦の心負荷早期検出法2016

    • Author(s)
      田中詩乃、小山理恵、佐々木由梨、金杉知宣、岩動ちづ子、福島明宗、菊池昭彦、杉山徹
    • Organizer
      第52回日本周産期新生児医学会
    • Place of Presentation
      富山国際会議場(富山県・富山市)
    • Year and Date
      2016-07-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] 妊産褥婦の心筋障害の早期検出法に関する研究2015

    • Author(s)
      田中詩乃、福島明宗、菊池昭彦、杉山徹、中居賢司
    • Organizer
      第35回日本ホルター・ノンインベイシブ心電研究会
    • Place of Presentation
      KOKUYO HALL(東京都・港区)
    • Year and Date
      2015-06-13
    • Related Report
      2015 Annual Research Report
  • [Presentation] Early Detection of Perinatal Period Myocardial Burden by High-Resolution Electrocardiography and2013

    • Author(s)
      Miyuki TERATA, Kenji NAKAI, Akimune FUKUSHIMA, Akihiko KIKUCHI, Toru SUGIYAMA
    • Organizer
      AOCOG 2013
    • Place of Presentation
      BANGKOK
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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