PITX1 expression and the telomerase control in an endometrial menstrual cycle and carcinogenic process
| Project/Area Number |
25462593
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 子宮内膜 / 子宮体癌 / テロメレース / 生殖 / 発癌 |
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| Outline of Final Research Achievements |
PITX1 protein was expressed in the tumor of the case with poorly-differentiated uterine cancer. However, no expression of PITX1 in more than 90% of the case with uterine cancer. Therefore, this might be associated with telomerase overexpression. PITX1 expression was detected in normal endometrium. Specific relationships could not be obtained regarding to menstrual cycle and carcinogenesis. I keep on analyzing the data that can be got throughout this period.
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Report
(4 results)
Research Products
(10 results)
