Effect of branched chain amino acid for sarcopenic dysphagia due to aging and disuse syndrome

• Project/Area Number: 25462677
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: The University of Tokyo
• Principal Investigator: Nito Takaharu 東京大学, 医学部附属病院, 講師 (60334372)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 嚥下障害 / 加齢 / 廃用症候群 / 分岐鎖アミノ酸 / 嚥下 / 必須アミノ酸

Outline of Final Research Achievements

There was no significant difference in the neuromuscular junction, fiber types and various receptors of the swallowing related muscles between the aged mouse group and the young mouse group.