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Clinical conditon and treatment of REM-related sleep apnea

Research Project

Project/Area Number 25462679
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Otorhinolaryngology
Research InstitutionUniversity of Occupational and Environmental Health, Japan

Principal Investigator

KITAMURA Takuro  産業医科大学, 医学部, 准教授 (60341509)

Co-Investigator(Kenkyū-buntansha) MIYAZAKI Soichiro  滋賀医科大学, 医学部, 特任教授 (20200157)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords睡眠時無呼吸症候群 / 睡眠呼吸障害 / レム関連睡眠時無呼吸 / 閉塞性睡眠時無呼吸
Outline of Final Research Achievements

REM-related sleep apnea is one of the subtypes of the OSA found frequently. Our result suggests that, compared to non REM-related sleep apnea, REM-related sleep apnea has low impact on the vigilance and sustainability of attention. Posture dependence had a negative influence on the expression of REM-related sleep apnea. Furthermore, expression of R had little effect from the anatomical factor of the upper airway. When considered in conjunction with that of REM sleep duration increases in the sleep latter half, REM-related sleep apnea patients tend to lack of subjective symptoms. However, recent studies proved that obstructive events during REM sleep highly associate with cardiovascular and metabolic outcomes independently of obstructive events during NREM sleep. It is important to establish a specific strategy that allows early detection and treatment for REM-related sleep apnea.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (6 results)

All 2015 2014 2013

All Presentation (6 results)

  • [Presentation] レム関連睡眠時無呼吸が覚醒度に与える影響について2015

    • Author(s)
      北村拓朗、宮崎総一郎、鈴木秀明
    • Organizer
      第39回日本睡眠学会
    • Place of Presentation
      栃木県総合文化センター(栃木県・宇都宮市)
    • Year and Date
      2015-07-02 – 2015-07-03
    • Related Report
      2014 Research-status Report
  • [Presentation] レム関連睡眠時無呼吸が覚醒度に与える影響について2015

    • Author(s)
      北村 拓朗 , 宮崎 総一郎 , 鈴木 秀明
    • Organizer
      日本睡眠学会第40回定期学術集会
    • Place of Presentation
      栃木県総合文化センター(栃木県、宇都宮市)
    • Year and Date
      2015-07-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] Clinical implications of REM related sleep apnea2015

    • Author(s)
      Takuro Kitamura, Soichiro Miyazaki
    • Organizer
      10th Sleep Respiratory Forum
    • Place of Presentation
      Ansan (Korea)
    • Year and Date
      2015-03-21
    • Related Report
      2014 Research-status Report
  • [Presentation] レムおよびノンレム期の睡眠呼吸障害が日中の覚醒度に与える影響の違いについて2014

    • Author(s)
      北村 拓朗 , 宮崎 総一郎 , 竹内 頌子 , 鈴木 秀明
    • Organizer
      第27回日本口腔・咽頭科学会総会ならびに学術講演会
    • Place of Presentation
      ホテルライフォート札幌(北海道・札幌)
    • Year and Date
      2014-09-11
    • Related Report
      2014 Research-status Report
  • [Presentation] レム関連睡眠時無呼吸に対する体位の影響2013

    • Author(s)
      北村 拓朗 , 宮崎 総一郎 , 加根村 隆 , 大川 匡子
    • Organizer
      第38回日本睡眠学会
    • Place of Presentation
      秋田キャッスルホテル
    • Related Report
      2013 Research-status Report
  • [Presentation] レム関連睡眠時無呼吸に影響する因子の検討2013

    • Author(s)
      北村 拓朗 , 宮崎 総一郎 , 鈴木 秀明
    • Organizer
      第26回日本口腔・咽頭科学会総会ならびに学術講演会
    • Place of Presentation
      ANAクラウンプラザホテルグランコート名古屋
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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