cancer-related small RNA as a biomarker for head and neck cancer
| Project/Area Number |
25462691
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kyorin University (2015)
Keio University (2013-2014) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IWAMARU Arifumi 慶應義塾大学, 医学部, 研究員 (00296592)
ZAMA Takeru 慶應義塾大学, 医学部, 特任講師 (30296719)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 頭頸部癌 / 診断 / 治療 / 頭頸部腫瘍 / 遺伝子 |
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| Outline of Final Research Achievements |
In this study, we have found that miR-196a could be a potential diagnostic biomarker for laryngeal cancer. Furthermore, results of our study suggested that this miR could be a promising future diagnostic target to treat laryngeal cancer.
Furthermore, we have investigated the human papillomvirus (HPV) expression in laryngeal papilloma. We found expressions of several unique HPV subtypes in laryngeal papilloma tissues. We further assessed the HPV subtypes combined with our abundant clinical background data of the patients, and found several promising findings. These unique and promising results offered multiple opportunities for us to present our data in Japan and US.
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Report
(4 results)
Research Products
(25 results)
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[Presentation] Laryngeal leukoplakia in non-smokers -who requires biopsy?-2014
Author(s)
Kosuke Uno, Koichiro Saito, Takeyuki Kono, Haruna Yabe, Kaoru Ogawa
Organizer
5th World Congress of IFHNOS (International Federation of Head and Neck Oncologic Societies) & Annual Meeting of the AHNS (American Head and Neck Society)
Place of Presentation
Kyoto, Japan
Year and Date
2014-04-14 – 2014-04-16
Related Report
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