Functional analysis of vitreous cells in intraocular proliferative disease towards a new treatment strategy
| Project/Area Number |
25462704
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Yamagata University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
YAMASHITA Hidetoshi 山形大学, 医学部, 教授 (90158163)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 硝子体細胞 / 増殖糖尿病網膜症 / 増殖硝子体網膜症 / 硝子体手術 / 樹状細胞 / ヒアルロナン / 網膜硝子体疾患 |
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| Outline of Final Research Achievements |
To investigate the the role of hyalocytes on pathogesis of the intra ocular proliferative diseases, we performed to construct the co-culture system with porcine vitreous derived cells, human vitreous derived cells and the other several kinds of cells include grial cell, endothelial cell and dendritic cell. Hyalocytes effect cell-cell interaction to those cells. It may be concerened that hyalocytes act to the pathogenesis via complicated cell-cell interactions.
Liquid based cytology could be applied to clinical vitreous analysi. There were several kinds of cells include dendritic cell in vitreous. Liquid based cytology could also enable clinical diagnosis (malignant lymphoma and vitreous amyloidosis) .
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Report
(4 results)
Research Products
(18 results)
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[Presentation] 周辺部硝子体処理適正化のための術中OCTによる周辺部硝子体の定量の試み2015
Author(s)
西塚 弘一,西 勝弘,武田 祐介,阿部 さち,桐井 枝里子,難波 広幸,菅野 彰,赤羽 梢,村上 敬憲,松下高幸，金子 優,山下 英俊
Organizer
第54回日本網膜硝子体学会総会
Place of Presentation
東京国際フォーラム（東京都港区）
Year and Date
2015-12-04
Related Report
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[Presentation] 硝子体細胞診の臨床的意義2015
Author(s)
西塚 弘一,成味 真梨,菅野 彰,金子 優,鈴木 俊紀,山川 光徳,山下 英俊,
Organizer
第69回日本臨床眼科学会総会
Place of Presentation
名古屋国際会議場（愛知県名古屋市）
Year and Date
2015-10-22
Related Report
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[Presentation] 空気タンポナーデを行った裂孔原性網膜剥離体する硝子体手術2014
Author(s)
西塚弘一,西勝弘,武田祐介,阿部さち,桐井枝里子,難波広幸,三浦瞳,菅野彰,成味真梨,赤羽梢,村上敬憲,金子優,山下英俊
Organizer
第53回網膜硝子体学会総会
Place of Presentation
大阪、大阪国際会議場
Year and Date
2014-11-28 – 2014-11-30
Related Report
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