The analysis of retinal morphological change and visual function using adaptive optics fundus imaging device and focal macular electroretinogram
| Project/Area Number |
25462710
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Nagoya University |
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Principal Investigator |
Ito Yasuki 名古屋大学, 医学(系)研究科(研究院), 准教授 (10313991)
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| Co-Investigator(Kenkyū-buntansha) |
Terasaki Hiroko 名古屋大学, 大学院医学系研究科, 教授 (40207478)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 補償光学眼底撮影装置 / 光干渉断層計 / 黄斑部局所網膜電図 / 視細胞 / 網膜血管 / AO / OCT / SLO |
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| Outline of Final Research Achievements |
In this study, fine retinal findings were analyzed using optical coherence tomography, adaptive optics fundus imaging device (AO), and focal macular electroretinogram (FMERG). The method to measure the cone density using automacic counting software with the manual correction for the reproducible measurement was investigated. It was shown that the amplitude of the FMERG were associated with the cone density. In the vascular imaging using AO, the method to visualize retinal artery wall and neovascular vessels in the eyes with proliferative diabetic retinopathy using offset mode of AO-scanning laser ophthalmoscope were investigated. Recovery of cone cell density in eyes after retinal detachment surgery and the decrease of the cone density in eyes with occult macular dystrophy were also investigated.
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Report
(4 results)
Research Products
(53 results)
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[Journal Article] Influence of Clinical Factors and Magnification Correction on Normal Thickness Profiles of Macular Retinal Layers Using Optical Coherence Tomography2016
Author(s)
Higashide T, Ohkubo S, Hangai M, Ito Y, Shimada N, Ohno-Matsui K, Terasaki H, Sugiyama K, Chew P, Li KK, Yoshimura N
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Journal Title
PLoS One
Volume: 11
Issue: 1
Pages: e0147782-e0147782
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Presentation] 強度近視眼の錐体計機能2014
Author(s)
高橋明子、伊藤逸毅、上野真治、寺﨑浩子
Organizer
第53回日本網膜硝子体学会総会
Place of Presentation
大阪国際会議場、大阪府大阪市
Year and Date
2014-11-29
Related Report
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[Presentation] ファイバー型光干渉断層計の開発2014
Author(s)
浅見 哲, 伊藤 逸毅, 杉田 糾, 西山 潤平, 並木 一, 東島 康裕, 小林 正彦, 西澤 典彦, 寺崎 浩子
Organizer
第118回日本眼科学会総会
Place of Presentation
帝国ホテル、東京都千代田区
Year and Date
2014-04-03
Related Report
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[Presentation] Parameters related to Choroidal thickness2013
Author(s)
Yasuki Ito, Kazuhiro Oiwa, Eiji Iwata, Akiko Takahashi, Tetsuhiro Yasuma, Kenichi Kawano, Nobuyuki Hamajima, Hiroko Terasaki
Organizer
The Association for Research in Vision and Ophthalmology
Place of Presentation
Seattle, USA
Related Report
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