Investigation of the mechanism of age-related macular degeneration using fundus autofluorescence associated with metabolism
| Project/Area Number |
25462724
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IIDA Tomohiro 東京女子医科大学, 眼科学教室, 教授 (50241881)
MARUKO Ichiro 東京女子医科大学, 眼科学教室, 特任講師 (10443871)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 黄斑変性 / 眼底自発蛍光 / 加齢 / 膜色素上皮 / 錐体細胞 / 網膜 / 自発蛍光 / 水晶体 / 白内障 / 緑色 / 青色 / 定量化 |
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| Outline of Final Research Achievements |
Aging of the retinal pigment epithelium is associated profoundly with age-related macular degeneration. Fundus autofluorescence is one of examination methods to evaluate activity of the retinal pigment epithelium. A method of quantitative measurement for fundus autofluorescence has been reported. However, it is difficult to perform quantitative measurement in elderly person because they have media opacity such as cataract.We developed the quantitative measurement system of fundus autofluorescence using green excitation laser and the reference in the optical system of scanning laser ophthalmoscope. Our system enable to measure fundus autofluorescence quantitatively in elderly person.
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Report
(4 results)
Research Products
(79 results)
