| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
In collaboration with Dr. Georgi Georgiev of Sofia University, Sofia, Bulgaria, we investigated the viscoelastic property of meibomian lipids. Our results showed that the elastic property of meibomian lipids is predominant in healthy meibum, while the viscous property of those lipids is predominant in diseased meibum. These novel findings suggest that we need to rethink the traditional idea that the tear film lipid layer has the function of preventing the evaporation of aqueous tears from the tear film. In addition, our findings revealed that the lower saccade of the eye facilitates tear film breakup and that there are five different types of tear film breakup pattern. Thus, we developed a topographical analysis system that can quantitatively assess the five different types of tear film breakup.
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