Multiethnic analysis of Behcet disease and its associated genes in Central Asia

• Project/Area Number: 25462731
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Health Sciences University of Hokkaido
• Principal Investigator: KITAICHI NOBUYOSHI 北海道医療大学, 個体差医療科学センター, 教授 (40431366)
• Co-Investigator(Kenkyū-buntansha): NAMBA Kenichi 北海道大学, 病院, 講師 (70333599)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: ベーチェット病 / 中央アジア / 遺伝子 / ゲノム / 疾患関連遺伝子 / ロシア

Outline of Final Research Achievements

I delivered special lectures about Behcet disease in Russia, Kazakhstan, and Kyrgyzstan, then made a diagnosis there. We understand that there are some Behcet patients in Russia and Kazakhstan. Most of the patients in Russia are not Russian but the minority groups of Dagestanian, Azerbaijani, Chechen, and Armenian. All of these 4 ethnic groups are Turki living in Caucasus region between Black Sea and Caspian Sea.Their clinical features are similar to those in other countries including Japan.
HLA Class I analysis showed that the frequency of HLA-B51 is high among the patients compared with healthy people. However, the exact frequency of HLA-B51 gene in healthy population is still unknown.

Research Products

• [Int'l Joint Research] ロシア医科学アカデミー(ロシア連邦)
• [Int'l Joint Research] カザフスタン・アスタナ医科大学(カザフスタン)
• [Int'l Joint Research] キルギス民族病院(キルギス)
• [Journal Article] HLA-B*51 carrier is susceptible to ocular symptoms of Behcet’s disease and its association becomes stronger towards east along Silk Road - a literature surve. (2016)
  • Author(s): Horie Y, Meguro A, Ohta T, Lee EB, Namba K, Mizuuchi K, Iwata D, Mizuki N, Ota M, Inoko H, Ishida S, Ohno S, Kitaichi N
  • Journal Title: Ocul Immunol Inflamm Volume: 印刷中
  • Peer Reviewed
• [Journal Article] Serial frequencies and clinical features of uveitis in Hokkaido, Japan (2016)
  • Author(s): Iwata D, Mizuuchi K, Aoki K, Horie Y, Kase S, Namba K, Ohno S, Ishida S,
  • Journal Title: Ocul Immunol Inflamm Volume: 印刷中
  • Peer Reviewed
• [Journal Article] Investigation of association between IL10 gene polymorphisms and Vogt-Koyanagi-Harada disease in a Japanese population (2016)
  • Author(s): Higashi K, Meouro A, Takeuchi M, Yamane T, Kitaichi N, Horie Y, Namba K, Ohno S, Nakao K, Sakamoto T, Sakai T, Tsuneoka H, Keino H, Okada AA, akeda A, Fukuhara T, Mashimo H, Ohguro N, Oono S, Enaida H, Okinami S, Mizuki N.
  • Journal Title: Ophthalmic Genet Volume: 印刷中
  • Peer Reviewed
• [Journal Article] Diagnostic efficacy of cell block method for vitreoretinal lymphoma. (2016)
  • Author(s): Kase S, Namba K, Iwata D, Mizuuchi K, Kitaichi N, Tagawa Y, Okada-Kanno H, Matsuno Y, Ishida S
  • Journal Title: Diagn Pathol Volume: 11 Issue: 1 Pages: 29-29
  • DOI: 10.1186/s13000-016-0479-1
  • NAID: 120005753722
  • Peer Reviewed / Open Access
• [Journal Article] Choroidal thickening prior to anterior recurrence in patients with Vogt-Koyanagi-Harada disease. (2016)
  • Author(s): Tagawa Y, Namba K, Mizuuchi K, Takemoto Y, Iwata D, Uno T, Fukuhara T, Hirooka K, Kitaichi N, Ohno S, Ishida S
  • Journal Title: Br J Ophthalmol Volume: 100 Issue: 4 Pages: 473-477
  • DOI: 10.1136/bjophthalmol-2014-306439
  • NAID: 120005753720
  • Peer Reviewed / Open Access
• [Journal Article] A Major Review: Current Aspects of Ocular Behçet's Disease in Japan. (2015)
  • Author(s): Namba K, Goto H, Kaburaki T, Kitaichi N, Mizuki N, Asukata Y, Fujino Y, Meguro A, Sakamoto S, Shibuya E, Yokoi K, Ohno S.
  • Journal Title: Ocul Immunol Inflamm. Volume: 23 Suppl 1 Issue: sup1 Pages: S1-S23
  • DOI: 10.3109/09273948.2014.981547
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Single center study on ethnic and clinical features of Behcet's disease in Moscow, Russia. (2015)
  • Author(s): Lennikov A, Alekberova Z, Goloeva R, Kitaichi N, Denisov L, Namba K, Takeno M, Ishigatsubo Y, Mizuki N, Nasonov E, Ishida S, Ohno S.
  • Journal Title: Clin Rheumatol Volume: 34 Issue: 2 Pages: 321-327
  • DOI: 10.1007/s10067-013-2442-9
  • Peer Reviewed
• [Journal Article] Role of macrophage migration inhibitory factor (MIF) in pollen-induced allergic conjunctivitis and pollen dermatitis in mice. (2015)
  • Author(s): Yuka Nagata, Yoko Yoshihisa, Kenji Matsunaga, Mati Ur Rehman,Nobuyuki Kitaichi, Tadamichi Shimizu
  • Journal Title: PLoS One Volume: 10 Issue: 2 Pages: 1-13
  • DOI: 10.1371/journal.pone.0115593
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 標準ビルベリーエキス含有食品摂取による眼疲労抑制効果 - ランダム化二重盲検プラセボ対照クロスオーバー試験 (2015)
  • Author(s): 小斉平麻里衣、影山将克、蒲原聖可、北市伸義
  • Journal Title: 臨床と治療 Volume: 43 Pages: 1741-1749
  • Peer Reviewed
• [Journal Article] 標準ビルベリー果実抽出物による眼疲労改善効果 (2015)
  • Author(s): 小斉平麻里衣、北市伸義
  • Journal Title: 薬理と治療 Volume: 43 Pages: 397-403
  • Peer Reviewed
• [Journal Article] ビルベリー果実由来特定アントシアニン摂取によるVDT負荷眼疲労の回復効果 (2015)
  • Author(s): 小斉平麻里衣、高尾久貴、葉山隆一、堀江幸弘、北市伸義
  • Journal Title: 薬理と治療 Volume: 43 Pages: 1339-1346
  • Peer Reviewed
• [Journal Article] ベーチェット病の病因探求の現状とインフリキシマブの効果 (2015)
  • Author(s): 北市伸義、梶田雅義
  • Journal Title: 日本医事新報 Volume: 4771 Pages: 62-62
• [Journal Article] 原発開放隅角緑内障患者に対する0.03%ビマトプロスト切り替えによる眼圧下降効果と安全性の検討 (2014)
  • Author(s): 仲 昌彦、山本麻梨亜、金 学海、横山千秋、石嶋 漢、北市伸義、大口剛司、新田卓也、新明康弘、陳 進輝、石田 晋
  • Journal Title: 臨床眼科 Volume: 68 Pages: 219-224
• [Journal Article] Amelioration of experimental autoimmune uveoretinitis by inhibition of glyceraldehyde derived-advanced glycation end product formation. (2014)
  • Author(s): Dong Z, Iwata D, Kitaichi N, Takeuchi M, Sato M, Endo N, Iwabuchi K, Ando R, Fukuhara J, Kinoshita S, Lennikov A, Kitamura M, Mizuuchi K, Kanda A, Noda K, Namba K, Yamagishi S, Ohno S, Ishida S
  • Journal Title: J Leukoc Biol Volume: 96 Issue: 6 Pages: 1077-1085
  • DOI: 10.1189/jlb.3a0513-288rrr
  • Peer Reviewed / Open Access
• [Journal Article] Intertypic modular exchanges of genomic segments by homologous recombination at universally conserved segments in human adenovirus species D (2014)
  • Author(s): Gabriel Gonzalez, Kanako O. Koyanagi, Koki Aoki, Nobuyoshi Kitaichi, Shigeaki Ohno, Hisatoshi Kaneko,d, Susumu Ishida, Hidemi Watanabe
  • Journal Title: Gene Volume: 547 Issue: 1 Pages: 10-17
  • DOI: 10.1016/j.gene.2014.04.018
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Increase of lysosomal phospholipase A2 in aqueous humor by uveitis. (2014)
  • Author(s): Hiraoka M, Abe A, Lennikov A, Kitaichi N, Ishida S, Ohguro H
  • Journal Title: Exp Eye Res Volume: 118. Pages: 13-19
  • DOI: 10.1016/j.exer.2013.09.018
  • Peer Reviewed
• [Journal Article] Behcet’s disease ocular attack score 24: evaluation of ocular disease activity before and after initiation of infliximab (2014)
  • Author(s): Kaburaki T, Namba K, Sonoda K, Kezuka T, Keino H, Fukuhara T, Kamoi K, Nakai K, Mizuki N, Ohguro N, Ohno S, Kitaichi N, Annabelle A, Watanabe T, Takeda A, Ishibashi T, Yawata K, Iwahashi C, Mochizuki M, Sugita S, Goto H, Takamoto M, Nakahara H, Kondo Y, Shibuya E, Kimura I
  • Journal Title: Jpn J Ophthalmol Volume: 58 Pages: 120-130
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of the long-term efficacy and safety of infliximab treatment for uveitis in Behçet's disease: a multicenter study. (2014)
  • Author(s): Takeuchi M, Kezuka T, Sugita S, Keino H, Namba K, Kaburaki T, Maruyama K, Nakai K, Hijioka K, Shibuya E, Komae K, Hori J, Ohguro N, Sonoda KH, Mizuki N, Okada AA, Ishibashi T, Goto H, Mochizuki M
  • Journal Title: Ophthalmology Volume: 121(10) Issue: 10 Pages: 1877-1884
  • DOI: 10.1016/j.ophtha.2014.04.042
  • Peer Reviewed / Open Access
• [Journal Article] Therapeutic effects of 0.1% tacrolimus eye drops for refractory allergic ocular diseases with proliferative lesion or corneal involvement (2014)
  • Author(s): Fukushima A, Ohashi Y, Ebihara N, Uchio E, Okamoto S, Kumagai N, Shoji J, Takamura E, Nakagawa Y, Namba K, Fujishima H, Miyazaki D
  • Journal Title: Br J Ophthalmol Volume: 98 Pages: 1023-1027
  • Peer Reviewed / Open Access
• [Journal Article] Single center study on ethnic and clinical features of Behcet's disease in Moscow, Russia (2014)
  • Author(s): Lennikov A, Alekberova Z, Goloeva R, Kitaichi N, Denisov L, Namba K, Takeno M, Ishigatsubo Y, Mizuki N, Nasonov E, Ishida S, Ohno S
  • Journal Title: Clin Rheumatol Volume: 未定
  • Peer Reviewed
• [Journal Article] Clinical features of human T lymphotropic virus type-1 associated uveitis in Hokkaido, Japan (2013)
  • Author(s): Kase S, Namba K, Kitaichi N, Iwata D, Ohno S, Ishida S
  • Journal Title: Jpn J Ophthalmo Volume: Vol.57 Issue: 4 Pages: 379-384
  • DOI: 10.1007/s10384-013-0244-x
  • NAID: 10031189427
  • Peer Reviewed
• [Journal Article] Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease (2013)
  • Author(s): Meguro A, Mizuki N(他18名)
  • Journal Title: Ann Rheum Dis Volume: 72(9) Issue: 9 Pages: 1510-1516
  • DOI: 10.1136/annrheumdis-2011-200288
  • Peer Reviewed
• [Journal Article] Induction of heat shock protein 70 ameliorates ultraviolet-induced photokeratitis in mice. (2013)
  • Author(s): Lennikov A, Kitaichi N, Kase S, Noda K, Horie Y, Nakai A, Ohno S, Ishida S
  • Journal Title: Int J Mol Sci Volume: 14 Issue: 1 Pages: 2175-2189
  • DOI: 10.3390/ijms14012175
  • NAID: 120005228266
  • Peer Reviewed
• [Journal Article] Trabecular meshwork depigmentation in Vogt-Koyanagi-Harada disease. (2013)
  • Author(s): Mizuuchi K, Kitaichi N, Namba K, Horie Y, Ishida S, Ohno S
  • Journal Title: Jpn J Ophthalmol Volume: 57 Issue: 3 Pages: 245-251
  • DOI: 10.1007/s10384-012-0229-1
  • NAID: 10031176278
  • Peer Reviewed
• [Journal Article] Stevens-Johnson syndrome/toxic epidermal necrolysis mouse model generated by using PBMCs and the skin of patients. (2013)
  • Author(s): Saito N, Yoshioka N, Abe R, Qiao H, Fujita Y, Hoshina D, Suto A, Kase S, Kitaichi N, Ozaki M, Shimizu H.
  • Journal Title: Journal of Allergy and Clinical Immunology Volume: 131 Issue: 2 Pages: 434-441
  • DOI: 10.1016/j.jaci.2012.09.014
  • Peer Reviewed
• [Journal Article] Identification of contamination in the American Type Culture Collection stock of human adenovirus type 8 by whole genome sequencing. (2013)
  • Author(s): Yamane S, Lee A, Hanaoka N, Gonzalez G, Kaneko H, Ishida S, Kitaichi N, Ohno S, Koyanagi K, Aoki K, Fujimoto T, Yawata N, Watanabe H.
  • Journal Title: J Virol Volume: 87 Issue: 2 Pages: 1285-1286
  • DOI: 10.1128/jvi.02875-12
  • Peer Reviewed
• [Journal Article] 院内感染を起こす新型ヒトアデノウイルスのバイオインフォマティクス (2013)
  • Author(s): 青木功喜、金子久俊、北市伸義、渡邉日出海、石田 晋、大野重昭
  • Journal Title: 日眼会誌 Volume: 117 Pages: 721-726
  • Peer Reviewed
• [Journal Article] 眼科 強膜炎 (2013)
  • Author(s): 有賀俊英、北市伸義
  • Journal Title: 今日の臨床サポート Volume: On line 書籍
• [Journal Article] Behcet 病 (2013)
  • Author(s): 北市伸義
  • Journal Title: 臨床眼科 増刊号 Volume: 67 Pages: 151-156
  • Peer Reviewed
• [Journal Article] 眼の健康科学―食品のサイエンス (2013)
  • Author(s): 北市伸義、石田晋
  • Journal Title: 眼科 Volume: 55 Pages: 717-722
  • NAID: 40019706988
• [Journal Article] アンチエイジング医学による疾病治療の可能性 アンチエイジング医学による加齢性眼疾患への介入 (2013)
  • Author(s): 北市伸義、石田晋
  • Journal Title: Geriatric Medicine（老年医学） Volume: 51 Pages: 693-696
• [Journal Article] 「目」. 他科協働とヘルスケア (2013)
  • Author(s): 北市伸義、大野重昭
  • Journal Title: 総合小児医療カンパニア Volume: 150 Pages: 150-155
• [Journal Article] コンタクトレンズ眼感染症 - アカントアメーバ角膜炎 (2013)
  • Author(s): 北市伸義、 大野重昭
  • Journal Title: 小児内科 Volume: 45 Pages: 1189-1190
• [Presentation] Therapy options of Behcet disease (2016)
  • Author(s): Kitaichi N
  • Organizer: Asia-Pacific Academy of Ophthalmology Congress (APAO) 2016
  • Place of Presentation: Taipei (Taiwan)
  • Year and Date: 2016-03-25
  • Int'l Joint Research / Invited
• [Presentation] Clinical effects of bilberry/blueberry anthocyanin on eye strain (2016)
  • Author(s): Kitaichi N
  • Organizer: SNOW (Sapporo Novel Ophthalmology Workshop)
  • Place of Presentation: ニューオータニ札幌（北海道・札幌市）
  • Year and Date: 2016-01-23
  • Int'l Joint Research
• [Presentation] Evolutionary analysis of human adenovirus-8 and -54, major causes of EKC (2015)
  • Author(s): Kitaichi N
  • Organizer: 2015 Seoul National - Hokkaido University Joint Symposium
  • Place of Presentation: Seoul (Korea)
  • Year and Date: 2015-11-20
  • Int'l Joint Research / Invited
• [Presentation] AAO (American Academy of Ophthalmology)2015 (2015)
  • Author(s): Kase S, Namba K, Mizuuchi K, Iwata D, Kitaichi N, Ohno S, Ishida S
  • Organizer: AAO (American Academy of Ophthalmology)2015
  • Place of Presentation: Las Vegas（USA）
  • Year and Date: 2015-11-14
  • Int'l Joint Research
• [Presentation] 光干渉断層計を用いたぶどう膜炎の嚢胞様黄斑浮腫の形状および治療反応性の解析 (2015)
  • Author(s): 岩田大樹、南場研一、橋本勇希、大野重昭、北市伸義、水内一臣、宇野友絵、鈴木智浩、石田 晋
  • Organizer: 第69回日本臨床眼科学会
  • Place of Presentation: 名古屋国際会議場（愛知県・名古屋市）
  • Year and Date: 2015-10-22
• [Presentation] 汎ぶどう膜炎を呈した多発消失性白点症候群の一例 (2015)
  • Author(s): 水内一臣、南場研一、齋藤航、橋本勇希、鈴木智浩、田川義晃、宇野友絵、岩田大樹、北市伸義、石田晋
  • Organizer: 第69回日本臨床眼科学会
  • Place of Presentation: 名古屋国際会議場（愛知県・名古屋市）
  • Year and Date: 2015-10-22
• [Presentation] Behcet’s diseas (2015)
  • Author(s): Kitaichi N
  • Organizer: Kazakh Eye Research Institute Seminars
  • Place of Presentation: Astana (Kazakhstan)
  • Year and Date: 2015-09-21
  • Int'l Joint Research / Invited
• [Presentation] ウニ外殻色素によるぶどう膜炎モデルの軽症化 (2015)
  • Author(s): 北市伸義、レニコフ アントン、南場研一、水内一臣、岩田大樹、大野重昭、石田 晋
  • Organizer: 第36回日本炎症・再生医学会
  • Place of Presentation: 虎ノ門ヒルズフォーラム（東京都特別区）
  • Year and Date: 2015-07-21
• [Presentation] 毒性終末糖化産物阻害薬による自己免疫性ぶどう膜網膜炎の軽症化 (2015)
  • Author(s): 董 震宇、北市伸義、野田航介、竹内正義、石田 晋
  • Organizer: 第36回日本炎症・再生医学会
  • Place of Presentation: 虎ノ門ヒルズフォーラム（東京都特別区）
  • Year and Date: 2015-07-21
• [Presentation] 視力予後が良好であった進行性網膜外層壊死の1例 (2015)
  • Author(s): 岩田大樹、南場研一、田川義晃、水内一臣、大野重昭、北市伸義、石田 晋、小笠原励起
  • Organizer: フォーサム2015
  • Place of Presentation: コングレコンベンションセンター（大阪府・大阪市）
  • Year and Date: 2015-07-10
• [Presentation] 眼内悪性リンパ腫の診断におけるセルブロック（細胞塊）標本の有用性 (2015)
  • Author(s): 加瀬 諭、南場研一、水内一臣、岩田大樹、北市伸義、石田 晋
  • Organizer: フォーサム2015
  • Place of Presentation: コングレコンベンションセンター（大阪府・大阪市）
  • Year and Date: 2015-07-10
• [Presentation] ロシアにおけるベーチェット病臨床像の検討 (2015)
  • Author(s): 北市伸義、ゴロエバ レジーナ、レニコフ アントン、アレクベローワ ゼンフィ－ラ、デニソフ レフ、堀江幸弘、南場研一、石田 晋、大野重昭
  • Organizer: フォーサム2015
  • Place of Presentation: コングレコンベンションセンター（大阪府・大阪市）
  • Year and Date: 2015-07-10
• [Presentation] ヒトアデノウイルス８型と54型の分子遺伝学的起源の検討 (2015)
  • Author(s): 北市伸義、山根翔太郎、ゴンザレス ガブリエル、パント ローラ、奥山雄一郎、金子久俊、青木功喜、小柳香奈子、渡邉日出海
  • Organizer: フォーサム2015
  • Place of Presentation: コングレコンベンションセンター（大阪府・大阪市）
  • Year and Date: 2015-07-10
• [Presentation] Changes of frequencies and clinical features of uveitis in Japan (2015)
  • Author(s): Kitaichi N, Iwata D, Mizuuchi K, Aoki K, Namba K, Ohno S, Ishida S
  • Organizer: Uveitis Workshop 2015
  • Place of Presentation: Cebu (Philippines)
  • Year and Date: 2015-05-15
  • Int'l Joint Research
• [Presentation] Fluorescein angiography (2015)
  • Author(s): Kitaichi N.
  • Organizer: Uveitis Workshop 2015 / Asia-Pacific Intraocular Inflammation Study Group Meeting
  • Place of Presentation: Cebu (Philippines)
  • Year and Date: 2015-05-15
  • Int'l Joint Research / Invited
• [Presentation] 流行性角結膜炎の起因ヒトアデノウイルス遺伝子解析 (2015)
  • Author(s): 青木功喜、大野重昭、北市伸義、日隈陸太郎、金子久俊、石田 晋.
  • Organizer: 第119回日本眼科学会総会
  • Place of Presentation: ロイトン札幌（北海道・札幌市）
  • Year and Date: 2015-04-16
• [Presentation] 若年性慢性虹彩毛様体炎の臨床像の検討 (2015)
  • Author(s): 宇野友絵、南場研一、水内一臣、岩田大樹、北市伸義、大野重昭、石田 晋
  • Organizer: 第119回日本眼科学会総会
  • Place of Presentation: ロイトン札幌（北海道・札幌市）
  • Year and Date: 2015-04-16
• [Presentation] Vogt-小柳―原田病再発例に対するシクロスポリン併用療法の検討 (2015)
  • Author(s): 水内一臣、南場研一、岩田大樹、宇野友絵、北市伸義、大野重昭、石田 晋
  • Organizer: 第119回日本眼科学会総会
  • Place of Presentation: ロイトン札幌（北海道・札幌市）
  • Year and Date: 2015-04-16
• [Presentation] Trabecular depigmentation in Vogt-Koyanagi-Harada disease (2015)
  • Author(s): Kitaichi N
  • Organizer: Asia-Pacific Academy of Ophthalmology Congress (APAO) 2015
  • Place of Presentation: Guangzhou (China)
  • Year and Date: 2015-04-04
  • Int'l Joint Research / Invited
• [Presentation] Sea urchin pigment ameliorates endotoxin-induced uveitis (2014)
  • Author(s): Kitaichi N
  • Organizer: 9th Japan-Korea International Symposium in Ophthalmology
  • Place of Presentation: Hokkaido university（Japan,Hokkaido）
  • Year and Date: 2014-12-01
• [Presentation] Amelioration of endotoxin-induced uveitis treated with the sea urchin pigment echinochrome (2014)
  • Author(s): Kitaichi N, Lennikov A, Noda K, Mizuuchi K, Namba K, Ohno S, Ishida S
  • Organizer: 16th International Conference on Behcet’s disease
  • Place of Presentation: Cite International Universitaire de Paris（France,Paris）
  • Year and Date: 2014-09-18 – 2014-09-20
• [Presentation] The appearance of antibodies to infliximab in the course of infliximab administration in Behçet’s disease (2014)
  • Author(s): Namba K, Mizuuchi K, Takemoto Y, Tagawa Y, Uno T, Fukuhara T, Ohno S, Kitaichi N, Ishida S
  • Organizer: 16th International Conference on Behcet’s disease
  • Place of Presentation: Cite International Universitaire de Paris（France,Paris）
  • Year and Date: 2014-09-18 – 2014-09-20
• [Presentation] Recombination hotspots enabling intertypic modular exchanges in human adenovirus species D (2014)
  • Author(s): Gonzalez G, Koyanagi KO, Aoki K, Kitaichi N, Ohno S, Kaneko H, Ishida S, Watanabe H
  • Organizer: 11th International Adenovirus Meeting
  • Place of Presentation: La jolla（USA,California）
  • Year and Date: 2014-07-16 – 2014-07-20
• [Presentation] Epidemiology of human adenovirus caused epidemic keratoconjunctivitis in recent Japan (2014)
  • Author(s): Kaneko H, Aoki K, Ohno S, Kitaichi N, Fujimoto T, Gonzalez G, Koyanagi KO, Watanabe H
  • Organizer: 11th International Adenovirus Meeting
  • Place of Presentation: La jolla（USA,California）
  • Year and Date: 2014-07-16 – 2014-07-20
• [Presentation] Evolutionary origins of human adenovirus types 8 and 54 (2014)
  • Author(s): Kitaichi N, Yamane S, Gonzalez G, Pantó L, Okuyama Y, Kaneko H, Wadell G, Gordon YJ, Yawata N, Albert Heim A, Koyanagi KO, Aoki A, Watanabe H
  • Organizer: 11th International Adenovirus Meeting
  • Place of Presentation: La jolla（USA,California）
  • Year and Date: 2014-07-16 – 2014-07-20
• [Presentation] Role of macrophage migration inhibitory factor (MIF) in pollen-induced allergic conjunctivitis and pollen dermatitis in mice (2014)
  • Author(s): Nagata Y, Yoshihisa Y, Matsunaga K, Kitaichi N, Shimizu T
  • Organizer: 73rd Annual Meeting, Society for Investigative Dermatology
  • Place of Presentation: Albuquerque（ New Mexico, USA）
  • Year and Date: 2014-05-07 – 2014-05-10
• [Presentation] Ethnic and clinical features of Behcet’s disease in Russia (2013)
  • Author(s): Kitaichi N
  • Organizer: 5th Japan and Korea Joint Meeting on Behcet’s Disease
  • Place of Presentation: Yokohama, Japan
  • Invited
• [Presentation] Induction of heat shock protein 70 ameliorates ultraviolet-induced photokeratitis in mice (2013)
  • Author(s): Kitaichi N
  • Organizer: 8th Annual Meeting of Hokkaido University - Seoul National University Joint Symposium on Ocular Inflammation
  • Place of Presentation: Seoul, Korea
  • Invited
• [Presentation] Amelioration of endotoxin-induced uveitis treated with an Iκ-B kinase βinhibitor in rats (2013)
  • Author(s): Kitaichi N
  • Organizer: 14th Annual Meeting of Korean Society for Behcet's disease
  • Place of Presentation: Seoul, Korea
  • Invited
• [Presentation] Clinical effects of astaxanthin on the eye (2013)
  • Author(s): Kitaichi N
  • Organizer: Samitivej Hospital Ophthalmology Meeting
  • Place of Presentation: Yokohama, Japan
  • Invited
• [Presentation] Clinical effects of astaxanthin on the eye (2013)
  • Author(s): Kitaichi N
  • Organizer: 8th Asia Pacific Conference on Clinical Nutrition
  • Place of Presentation: Tokyo, Japan
  • Invited
• [Presentation] HTLV-I associated uveitis (2013)
  • Author(s): Kitaichi N
  • Organizer: International Workshop on Granulomatous Uveitis and Ocular Behcet's disease and Asia-Pacific Intraocular Inflammation Study Group
  • Place of Presentation: Kaohsiung, Taiwan
  • Invited
• [Presentation] Induction of heat shock protein 70 ameliorates ultraviolet-induced photokeratitis in mice (2013)
  • Author(s): Kitaichi N, Lennikov A, Kase S, Noda K, Horie Y, Ohno S, Ishida S
  • Organizer: Association for Research in Vision and Ophthalmology Annual Meeting
  • Place of Presentation: Seattle, WA, USA
• [Presentation] Clinical features of Vogt-Koyanagi-Harada’s disease. 7th Korean Uveitis Conference (2013)
  • Author(s): Ohno S, Namba K, Kitaichi N
  • Organizer: 8th Annual Meeting of Hokkaido University - Seoul National University Joint Symposium on Ocular Inflammation
  • Place of Presentation: Seoul, Korea
  • Invited
• [Presentation] 分子から解き明かすアデノウイルス結膜炎 (2013)
  • Author(s): 北市伸義
  • Organizer: 北海道眼炎症免疫セミナー
  • Place of Presentation: 札幌
  • Invited
• [Presentation] “目と鼻の先”の眼炎症論 (2013)
  • Author(s): 北市伸義
  • Organizer: 北海道耳鼻咽喉科サマーセミナー
  • Place of Presentation: 札幌
  • Invited
• [Presentation] ドライアイ患者の角膜痛覚に対するレバミピド点眼の効果 (2013)
  • Author(s): 田川義晃、北市伸義、大口剛司、山本哲平、水内一臣、田川義継、石田 晋
  • Organizer: 第67回臨床眼科学会
  • Place of Presentation: 横浜
• [Presentation] ぶどう膜炎に続発した血管増殖性網膜腫瘍の2症例 (2013)
  • Author(s): 水内一臣、南場研一、齋藤 航、堀江幸弘、田川義晃、宇野友絵、竹本裕子、福原崇子、北市伸義、石田 晋
  • Organizer: 第67回臨床眼科学会
  • Place of Presentation: 横浜
• [Presentation] HSP70誘導による紫外線角膜障害軽症化とそのメカニズム (2013)
  • Author(s): 北市伸義
  • Organizer: 第14回 GGA-HSP 勉強会
  • Place of Presentation: 東京
• [Presentation] 脈絡膜新生血管を合併しベバシズマブ硝子体注射を要した小児原田病の1例 (2013)
  • Author(s): 田川義晃、南場研一、齋藤 航、水内一臣、北市伸義、大野重昭、石田 晋
  • Organizer: フォーサム2013大阪
  • Place of Presentation: 大阪
• [Presentation] ぶどう膜炎における網羅的糖差解析 (2013)
  • Author(s): 南場研一、北市伸義、安藤 亮、竹本裕子、水内一臣、堀江幸弘、大野重昭、天野麻穂、西村紳一郎、石田 晋
  • Organizer: 第117回日本眼科学会
  • Place of Presentation: 東京
• [Presentation] 眼内リソゾームホスホリパーゼA2(LPLA2)活性化機序の検討 (2013)
  • Author(s): 平岡美紀、阿部 晃、北市伸義、Anton Lennikov、石田 晋、大黒 浩
  • Organizer: 第117回日本眼科学会
  • Place of Presentation: 東京
• [Book] 日本抗加齢医学会認定テキスト 第3版 アンチエイジング医学の基礎と臨床 (2015)
  • Author(s): 北市伸義、石田 晋
  • Total Pages: 447
  • Publisher: メジカルビュー社
• [Book] 治療薬ハンドブック 2015 (2015)
  • Author(s): 北市伸義、大野重昭
  • Total Pages: 321
  • Publisher: 株式会社じほう
• [Book] 今日の臨床サポート (2014)
  • Author(s): 有賀俊英、北市伸義
  • Publisher: エルセビア・ジャパン
• [Book] 治療薬ハンドブック 2014 (2014)
  • Author(s): 北市伸義、大野重昭
  • Total Pages: 1500
  • Publisher: じほう
• [Book] 専門医のための眼科クオリファイ21 眼救急疾患スクランブル (2014)
  • Author(s): 北市伸義
  • Total Pages: 380
  • Publisher: 中山書店
• [Book] Cellular Response to Physical Stress and Therapeutic Application (2013)
  • Author(s): Kitaichi N
  • Total Pages: 204
  • Publisher: Nova Biomedical
• [Book] 専門医のための眼科診療クオリファイ16 糖尿病眼合併症の新展開 (2013)
  • Author(s): 北市伸義
  • Total Pages: 265
  • Publisher: 中山書店
• [Book] 今日の治療指針2013 私はこう治療している (2013)
  • Author(s): 北市伸義
  • Total Pages: 2064
  • Publisher: 医学書院
• [Book] 治療薬ハンドブック 2013 (2013)
  • Author(s): 北市伸義、大野重昭
  • Total Pages: 1524
  • Publisher: じほう