Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Outline of Final Research Achievements |
We successfully conducted transplantation of a hiPSC-RPE cell sheet into a patient with AMD as the first-in-human trial using hiPSCs. AMD lesion, which is 3.0 mm in diameter, requires a 3.0 x 3.0 mm graft, however the surgical device in current use is possible to transplant less than 1.3 x 3.0 mm grafts. Therefore, we produced a surgical device which is possible to transplant a 3.0 x 3.0 mm graft via 1.5 mm scleral wound. The suction port of the device was designed on the lateral side in the insertion direction and the inside of device was processed to be able to store a 3.0 x 3.0 mm grafts. The device is possible to transplant grafts larger than scleral wound.
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