the role of versican in skin and wound healing
Project/Area Number |
25462801
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Plastic surgery
|
Research Institution | Keio University |
Principal Investigator |
Aramaki Noriko 慶應義塾大学, 医学部(信濃町), 講師 (80365311)
|
Co-Investigator(Kenkyū-buntansha) |
貴志 和生 慶應義塾大学, 医学部(信濃町), 教授 (40224919)
|
Project Period (FY) |
2013-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | versican / wound healing / scarless wound / versikine / 血管新生 / 創傷治癒 / 細胞外マトリックス / vesican / 皮膚 |
Outline of Final Research Achievements |
In a wound-healing model using Vcanhdf/+ mice, we found that neovascularization is more strongly suppressed in Vcanhdf/+ mice than WT mice.This same phenomenon was observed using the cancer model in this study, suggesting that versican may have an important role in neovascularization. In the future, we plan to conduct functional analyses of versican on neovascularization.
|
Report
(5 results)
Research Products
(13 results)