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Elucidation of the central nervous system mechanisms that control oral-facial-tongue sensation and mastication

Research Project

Project/Area Number 25462903
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Functional basic dentistry
Research InstitutionThe Nippon Dental University

Principal Investigator

SATOH Yoshihide  日本歯科大学, 新潟生命歯学部, 准教授 (20287775)

Co-Investigator(Renkei-kenkyūsha) YAMAMURA Kensuke  新潟大学, 歯学部, 教授 (90272822)
Research Collaborator YAJIMA Eriko  
NAGAMINE Yasuhiro  
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords口腔・顔面・舌感覚 / 咀嚼 / 嚥下 / 中枢神経機構
Outline of Final Research Achievements

It was revealed from this study as follows. 1. Stimulation of the red nucleus (RN) facilitated the low-threshold afferent-evoked jaw-opening reflex (JOR) and suppressed the high-threshold afferent-evoked JOR. 2. The RN-induced suppression of the high-threshold afferent-evoked JOR is mediated by a relay in the lateral reticular nucleus. 3. The RN-induced facilitation of the low-threshold afferent-evoked JOR is mediated by a relay in the vestibular nucleus. 4. The raphe magnus nucleus-induced suppression of the high-threshold afferent-evoked JOR is mediated by a relay in the RN. 5. The red nucleus is involved in the control of swallowing.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (17 results)

All 2016 2015 2014 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 3 results,  Open Access: 1 results) Presentation (11 results) Remarks (2 results)

  • [Journal Article] Role of the vestibular nuclear complex in facilitating the jaw-opening reflex following stimulation of the red nucleus2016

    • Author(s)
      Satoh Y, Ishizuka K, Takahashi M, Iwasaki S.
    • Journal Title

      Neuroscience Research

      Volume: 未定 Pages: 29-36

    • DOI

      10.1016/j.neures.2016.02.008

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Suppression of the swallowing reflex by stimulation of the red nucleus2015

    • Author(s)
      Satoh Y, Tsuji K, Tsujimura T, Ishizuka K, Inoue M.
    • Journal Title

      Brain Research Bulletin

      Volume: 116 Pages: 25-33

    • DOI

      10.1016/j.brainresbull.2015.05.007

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Role of the red nucleus in suppressing the jaw-opening reflex following stimulation of the raphe magnus nucleus2014

    • Author(s)
      Satoh Y, Ishizuka K, Iwasaki S.
    • Journal Title

      Neuroscience Research

      Volume: 85 Pages: 12-19

    • DOI

      10.1016/j.neures.2014.05.010

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Role of lateral reticular nucleus in suppressing the jaw-opening reflex following stimulation of the red nucleus2014

    • Author(s)
      Satoh Y, Yjima E, Ishizuka K, Iwasaki S.
    • Journal Title

      Neuroscience Research

      Volume: 80巻 Pages: 10-16

    • DOI

      10.1016/j.neures.2013.12.003

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Involvement of the vestibular nuclear complex in the facilitation induced by stimulation of the red nucleus on the jaw-opening reflex2016

    • Author(s)
      Satoh Y Ishizuka K, Takahashi M, Iwasaki S
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌
    • Year and Date
      2016-03-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] Role of the vestibular nuclear complex in facilitating the jaw-opening reflex following stimulation of the red nucleus2016

    • Author(s)
      Satoh Y, Ishizuka K, Takahashi M, Iwasaki S
    • Organizer
      日本歯科大学歯学会English発表会
    • Place of Presentation
      新潟
    • Year and Date
      2016-03-03
    • Related Report
      2015 Annual Research Report
  • [Presentation] ラット赤核刺激による開口反射の促通における前庭神経核の役割2015

    • Author(s)
      佐藤義英, 石塚健一, 高橋睦, 岩﨑信一
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] Role of the vestibular nuclear complex in facilitating the jaw-opening reflex following stimulation of the red nucleus2015

    • Author(s)
      Satoh Y, Ishizuka K, Iwasaki S.
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] Suppression of the swallowing reflex by stimulation of the red nucleus in rats2015

    • Author(s)
      Satoh Y, Tsuji K, Tsujimura T, Ishizuka K, Inoue M.
    • Organizer
      平成27年度日本歯科大学歯学会大会・総会
    • Place of Presentation
      新潟
    • Year and Date
      2015-06-06
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effect of the swallowing reflex by stimulation of the red nucleus in rats2014

    • Author(s)
      Satoh Y, Tsuji K, Tsujimura T, Inoue M
    • Organizer
      第44回北米神経科学大会
    • Place of Presentation
      Whashington D.C.
    • Year and Date
      2014-11-18
    • Related Report
      2014 Research-status Report
  • [Presentation] 赤核刺激による嚥下反射の抑制2014

    • Author(s)
      佐藤義英,辻光順,辻村恭憲,井上誠,石塚健一,岩﨑信一
    • Organizer
      第56回歯科基礎医学会 学術大会・総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] Role of the red nucleus in suppressing the jaw-opening reflex following stimulation of the raphe magnus nucleus2014

    • Author(s)
      Satoh Y, Ishizuka K, Iwasaki S
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-11
    • Related Report
      2014 Research-status Report
  • [Presentation] Involvement of the lateral reticular nucleus in the suppression induced by stimulation of the red nucleus on the jaw-opening reflex

    • Author(s)
      Satoh Y, Yajima E, Ishizuka K, Nagamine Y, Iwasaki S.
    • Organizer
      36th International Congress of Physiological Sciences
    • Place of Presentation
      International convention centre (Birmingham)
    • Related Report
      2013 Research-status Report
  • [Presentation] 赤核刺激による開口反射の変調における外側網様核の関与

    • Author(s)
      佐藤義英,石塚健一,岩﨑信一
    • Organizer
      第55回歯科基礎医学会大会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Related Report
      2013 Research-status Report
  • [Presentation] Involvement of the red nucleus in the suppression induced by stimulation of the raphe magnus nucleus on the jaw-opening reflex

    • Author(s)
      Satoh Y, Ishizuka K, Iwasaki S.
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島市)
    • Related Report
      2013 Research-status Report
  • [Remarks]

    • URL

      http://www.ngt.ndu.ac.jp/about/course/basic03/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 日本歯科大学新潟生命歯学部生理学講座ホームページ

    • URL

      http://www.ngt.ndu.ac.jp/guide/kouza/kiso03.html

    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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