| Project/Area Number |
25462954
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
Okiji Takashi 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (80204098)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | ケイ酸カルシウム / 歯内療法 / 覆髄 / リン酸カルシウム / アパタイト / MTA / PBS / CS / 歯内療法用材料 / 再石灰化 / 覆髄材 / 生体機能効果 / 動物実験 / 生体機能性 / 齲蝕制御 / 歯髄修復 / 生体親和性 / 歯質再構築 |
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| Outline of Final Research Achievements |
To evaluate the Ca2+-releasing, alkalizing, and apatite-like surface precipitate-forming abilities of a prototype tricalcium silicate cement. The chemical compositions were analyzed with EPMA. The pH and Ca2+ concentrations immersed were measured. The surface precipitates formed on the materials immersed in PBS were analyzed with EPMA and XRD. The prototype cement contained Ca, Si, and Zr as major elemental constituents, whereas it did not contain some metal elements that were detected in the other materials. The Ca2+ concentrations and pH of the immersion water samples exhibited the following order: WMTA = prototype cement > TheraCal LC (P <0.05). XRD peaks corresponding to hydroxyapatite were detected in the precipitates produced by the prototype cement and WMTA. The prototype tricalcium silicate cement exhibited similar Ca2+-releasing, alkalizing, and apatite-like precipitate-forming abilities to WMTA.
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