The development of a new dental adhesive restoration to reduce dentin endogenous matrix metalloproteinases activity.

Research Project

Project/Area Number	25462959
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Conservative dentistry
Research Institution	Kagoshima University (2015) Okayama University (2013-2014)
Principal Investigator	Nishitani Yoshihiro 鹿児島大学, 医歯学域歯学系, 教授 (60325123)
Co-Investigator(Kenkyū-buntansha)	YOSHIYAMA Masahiro 岡山大学, 大学院医歯薬学総合研究科, 教授 (10201071)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000) Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	接着歯学 / 象牙質 / マトリックスメタロプロテアーゼ / レジン
Outline of Final Research Achievements	For the purpose of establishing a dental adhesive methods to reduce the re-treatment after the resin composite treatment, without lowering the adhesive performance, it was examined a new adhesive system to reduce the dentin MMPs activity. As a result, the possibility of achieving the purpose by adding diethylene triamine pentaacetic acid is a crosslinking agent that can be applied clinically.

Report

(4 results)