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Dose the incretin related-drug have an influence on the onset mechanism of apical periodontitis and marginal periodontitis?

Research Project

Project/Area Number 25462964
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionKagoshima University

Principal Investigator

SAKUTA Tetsuya  鹿児島大学, 医歯学域附属病院, 助教 (20284888)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords糖尿病 / 歯周病 / 歯髄炎 / 歯内治療学
Outline of Final Research Achievements

It is said Japan has approximately 9 million diabetics (including the person that diabetes is strongly soubted and the person who can not deny possibility of diabetes)(The National Health and Mutririon Survey in Japan), and there is a person receiving an injection of insulin and/or treated for oral diabetic agents, but the thing which a patient of approximately 80% takes in medicine is medicine called the incretin now. The incretin medications have not only I a state of diabetes better but also various action (potection of heart and/or kidney). I found the finding in vitro that the action which may improve periodontal disease and pulpitis to the medicine.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (1 results)

All 2015

All Presentation (1 results)

  • [Presentation] ヒト歯肉線維芽細胞におけるMMP-1産生に対するGLP-1受容体作動薬の調節作用2015

    • Author(s)
      作田 哲也
    • Organizer
      第8回(2015年)鹿児島大学大学院医歯学総合研究科 口腔先端科学教育研究センター 歯系研究発表会
    • Place of Presentation
      鹿児島大学桜ヶ丘キャンパス鶴陵会館大ホール(鹿児島県鹿児島市)
    • Year and Date
      2015-12-05
    • Related Report
      2015 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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