| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Outline of Final Research Achievements |
It was reported that Surface Pre-Reacted Glass ionomer (S-PRG) filler released multiple ions such as fluoride, strontium and boron, and contributed to inhibit demineralization, as well as it may have antimicrobial effects on oral bacteria.
In this study, we could demonstrated that culture medium containing S-PRG eluate showed predominant antibacterial effects on polymicrobial biofilm model which contained multiple species of oral bacteria in compared with culure medium with NaF. Futher, sixty-minutes' application of the S-PRG eluate on formed polymicrobial biofilms showed also remarkable antibacterial effects.
These results indicate that the S-PRG eluate will be useful for oral health by using delivery systems such as tray-technique.
|
