Effects of dental materials containing multiple ions releasing filler against viabilities of oral biofilms
Project/Area Number |
25462975
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Conservative dentistry
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Research Institution | Kanagawa Dental College |
Principal Investigator |
MUKAI Yoshiharu 神奈川歯科大学, 歯学研究科(研究院), 准教授 (40247317)
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Co-Investigator(Kenkyū-buntansha) |
HAMADA Nobushiro 神奈川歯科大学, 大学院歯学研究科, 教授 (20247315)
TOMIYAMA Kiyoshi 神奈川歯科大学, 大学院歯学研究科, 講師 (90237131)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | バイオフィルム / S-PRGフィラー / 脱灰抑制 / 抗菌効果 / イオン徐放性微粒子 / バイオフィルムモデル / 齲蝕予防 |
Outline of Final Research Achievements |
It was reported that Surface Pre-Reacted Glass ionomer (S-PRG) filler released multiple ions such as fluoride, strontium and boron, and contributed to inhibit demineralization, as well as it may have antimicrobial effects on oral bacteria. In this study, we could demonstrated that culture medium containing S-PRG eluate showed predominant antibacterial effects on polymicrobial biofilm model which contained multiple species of oral bacteria in compared with culure medium with NaF. Futher, sixty-minutes' application of the S-PRG eluate on formed polymicrobial biofilms showed also remarkable antibacterial effects. These results indicate that the S-PRG eluate will be useful for oral health by using delivery systems such as tray-technique.
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] Effects of resin-based temporary filling materials against dentin demineralization2016
Author(s)
Shiiya T, Tomiyama K, Iizuka J, Hasegawa H, Kuramochi E, Fujino F, Ohashi K, Nihei T, Teranaka T, Mukai Y
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Journal Title
Dental Materials Journal
Volume: 35
Issue: 1
Pages: 70-75
DOI
NAID
ISSN
0287-4547, 1881-1361
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Presentation] Anti-Demineralization Effect of Novel S-PRG Filler Containing Varnishes on Dentin2015
Author(s)
Toru Shiiya, Aiko Kataoka, Fukue Fujino, Kiyoshi Tomiyama, Junko Iizuka, Haruhiko Hasegawa, Erika Kuramochi, Katsura Ohashi, Tomotaro Nihei, Yoshiharu Mukai
Organizer
Academy of Dental Materials 2015 Annual Meeting
Place of Presentation
Maui, USA
Year and Date
2015-10-08
Related Report
Int'l Joint Research
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