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biological evaluation of curcumin contributions for the bone formation

Research Project

Project/Area Number 25462988
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionNiigata University

Principal Investigator

Akiba Nami  新潟大学, 医歯学総合病院, 助教 (00584591)

Co-Investigator(Kenkyū-buntansha) 加来 賢  新潟大学, 医歯学系, 准教授 (30547542)
魚島 勝美  新潟大学, 医歯学系, 教授 (50213400)
秋葉 陽介  新潟大学, 医歯学総合病院, 講師 (70547512)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords健康食品 / 骨粗鬆症 / インプラント / クミン / 骨増生 / 機能性食品 / 抗酸化作用 / 骨欠損修復
Outline of Final Research Achievements

Osteoporosis is one of the risk factor for implant therapy. Curcumin is known as a functional healthy food and able to remove active oxygen spices. Curcumin thought to be contributed to help bone formation and save people from osteoporosis. The aim of this study is to elucidate the mechanisms of acceleration for bone formation by curcumin. We fed curcumin to the normal rat and OVX rat, then observed maxillary cylindrical cavity healing, calvarias defect and femoral defect. Among these all samples, there are no significant difference could be seen.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (1 results)

All 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results)

  • [Journal Article] Biological Evaluation of Implant Drill Made from Zirconium Dioxide2017

    • Author(s)
      Y Akiba, K Eguchi, N Akiba, K Uoshima
    • Journal Title

      Clin Implant Dent Relat Res

      Volume: 19(2) Issue: 2 Pages: 306-315

    • DOI

      10.1111/cid.12452

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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