| Project/Area Number |
25463006
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MURATA Hiroshi 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (40229993)
TANAKA Mihoko 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (00304957)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 口腔顔面痛 / 疼痛過敏 / 慢性疼痛 / eccentric運動 / 顎運動 / 低強度かみしめ / 頚部筋活動 / 三叉神経 / 咀嚼筋痛 / 慢性痛 / 下顎運動 / 電気刺激 / 持続咬みしめ |
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| Outline of Final Research Achievements |
Etiology of hyperalgesia in chronic orofacial pain patients, especially the possible contribution of jaw movements to hyperalgesia, was investigated. Single experimental low-level jaw clenching did not induce orofacial hyperalgesia, but inhibited pain sensitivity evaluated by temporal summation. Prior-load of eccentric jaw exercise increased pain sensitivity after the subsequent low-level jaw clenching, and different levels in prior eccentric exercise evoked different condition of pain sensitivity. These findings may suggest that prior-load of eccentric jaw exercise can evoke hyperalgesic condition in orofacial region. Character of image analysis of food particles as a method of evaluation for stomatognathic function, and sensory-motor interactions between the intra-oral sensory system and neck muscle activity, were also investigated.
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