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Development of new generation of bioactive implant

Research Project

Project/Area Number 25463008
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionNagasaki University

Principal Investigator

WATANABE Etsuko  長崎大学, 医歯薬学総合研究科(歯学系), 客員研究員 (00325664)

Co-Investigator(Kenkyū-buntansha) WATANABE Ikuya  長崎大学, 医歯薬学総合研究科(歯学系), 教授 (00274671)
KUROSHIMA Shinichiro  長崎大学, 病院(歯学系), 講師 (40443915)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsバイオガラス / ジルコニア / バイオグラス
Outline of Final Research Achievements

In this study, the zirconia discs coated with zirconia beads and coated with the 45s5 bioactive glass sol, made by the sol-gel method. Homogeneous and thin BG layer was successfully coated on the surface after blasting the substrates by alumina powder and dipping in the bioactive glass sol and sintering at 1200°C for 1 h. strongly adhered thin BG layer covered all surface after sintering. MC3-T3-E1 cells were used for cell morphology and cell viability evaluations. The Bioactive glass coated substrates showed higher viability among all samples. Bioactive glass was coated on the zirconia successfully by dipping the substrates into the bioactive glass sol.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (14 results)

All 2015 2014 2013 Other

All Int'l Joint Research (1 results) Journal Article (6 results) (of which Peer Reviewed: 6 results,  Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Int'l Joint Research: 3 results)

  • [Int'l Joint Research] Systems Biology Institute(Iran)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Joining characteristics of titanium-based orthodontic wires connected by laser and electrical welding methods2015

    • Author(s)
      Matsunaga J, Watanabe I, Nakao N, Watanabe E, Elshahawy W, Yoshida N
    • Journal Title

      J Mater Sci- Mater Med

      Volume: 26 Pages: 5391-5399

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Evaluation of glass transition temperature and dynamic mechanical properties of autopolymerized hard direct denture reline resins2015

    • Author(s)
      Takase K, Watanabe I, Kurogi T, Murata H
    • Journal Title

      Dent Mater J

      Volume: 34 Pages: 211-218

    • NAID

      130005062404

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of migrated foreign bodies in the maxillae by X-ray fluorescence spectrometry2014

    • Author(s)
      Matsuda S, Ohba S, Yoshimura H, Kobayashi J, Watanabe I, Sano K
    • Journal Title

      Journal of Craniofacial Surgery

      Volume: 25 Pages: 233-235

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Influence of composition and powder/liquid ratio on setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins based on methyl methacrylate and ethylene glycol dimethacrylate2014

    • Author(s)
      Okuyama Y, Shiraishi T, Yoshida K, Kurogi T, Watanabe I, Murata H
    • Journal Title

      Dent Mater J

      Volume: 33 (4) Pages: 522-529

    • NAID

      130004679322

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Comparison of conventional and new-generation nickel-titanium files in regard to their physical properties2014

    • Author(s)
      Tsujimoto M, Irifune Y, Tsujimoto Y, Yamada S, Watanabe I, Hayashi Y
    • Journal Title

      J Endodont

      Volume: 40 (11) Pages: 1824-1829

    • NAID

      120006986368

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of laser emission parameters on mechanical and physical properties of cast pure titanium2014

    • Author(s)
      Hayashi T, Watanabe I, Kurogi T, Shiraishi T, Murata H
    • Journal Title

      J Spectroscopy

      Volume: Dec 2014 Pages: 1-8

    • NAID

      120006986274

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] Mechanical and biological performance of glass ionomer cement modified by bioactive glass nanoparticles2015

    • Author(s)
      Valanezhad A, Shiraishi T, Sawase T, Watanabe I
    • Organizer
      27th Symposium and Annual Meeting of The International Society for Ceramics in Medicine
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evaluation of the bone regeneration potential of bioactive glass enhanced with PRP and BMP2 in an augmentation model. A comparative study2015

    • Author(s)
      Nourani M, Sumita Y, Valanezhad A, Watanabe I, Asahina I
    • Organizer
      The 15th Meeting of Iranian Academy of Periodontology
    • Place of Presentation
      Tehran, Iran
    • Year and Date
      2015-10-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of bioactive glass nanoparticles on glass ionomer cement properties2015

    • Author(s)
      Valanezhad A, Watanabe I
    • Organizer
      International Porous Powder Materials
    • Place of Presentation
      Izmir, Turkey
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 歯科用ジルコニア材料の高速切削性に関する研究2014

    • Author(s)
      中尾紀子,迫田 敏,渡邊郁哉
    • Organizer
      第64回秋期日本歯科理工学会大会
    • Place of Presentation
      広島(アステールプラザ)
    • Year and Date
      2014-10-04 – 2014-10-05
    • Related Report
      2014 Research-status Report
  • [Presentation] 電気的/レーザー溶接法による矯正用ワイヤー接合法の評価2014

    • Author(s)
      中尾紀子,松永淳子,渡邊悦子,吉田教明,渡邊郁哉
    • Organizer
      第63回春期日本歯科理工学会大会
    • Place of Presentation
      東京(タワーホール舟堀)
    • Year and Date
      2014-04-12 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 矯正用チタン合金とステンレス合金ワイヤーの電気的溶接2013

    • Author(s)
      中尾紀子,松永淳子,渡邊悦子,吉田教明,渡邊郁哉
    • Organizer
      第61回春期日本歯科理工学会大会
    • Place of Presentation
      東京 (タワーホール船堀)
    • Related Report
      2013 Research-status Report
  • [Presentation] 矯正用チタン合金ワイヤーの電気的溶接法による接合2013

    • Author(s)
      中尾紀子,松永淳子,渡邊悦子,吉田教明,渡邊郁哉
    • Organizer
      第62回秋期日本歯科理工学会大会
    • Place of Presentation
      新潟 (日本歯科大学新潟生命歯学部校舎)
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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