Fabrication of Adhesive Apatite Cement

Research Project

Project/Area Number	25463051
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Dental engineering/Regenerative dentistry
Research Institution	Kyushu University
Principal Investigator	Munar ML 九州大学, 歯学研究科(研究院), 研究員 (50432919)
Co-Investigator(Kenkyū-buntansha)	Kunio Ishikawa 九州大学, 大学院歯学研究院, 教授 (90202952)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000) Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000) Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	アパタイトセメント / 粘着性 / アテロコラーゲン / 骨
Outline of Final Research Achievements	In order to fabricate apatite cement which enable to adhere to wetting bone, adhesive property was given to apatite cement. The apatite cement was composed of disodium hydrogen phosphate solution as liquid part and TTCP-DCPD powder as powder part. Atelocollagen was added into liquid part as thickener. The adhesive strength of apatite cement was increased as a function of atelocollagen concentration. However, even though several positive phenomenon were observed, the maximum adhesive strength was far weaker than the practical using strength. Further studies are needed in order to reinforce the bonding and adhesive strength to bone and apatite.