| Project/Area Number |
25463054
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Dental engineering/Regenerative dentistry
|
|---|
| Research Institution | Tokyo Medical University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
CHIKAZU Daichi 東京医科大学, 医学部, 教授 (30343122)
Matsuo Akira 東京医科大学, 医学部, 教授 (70229417)
Satomi Takafumi 東京医科大学, 医学部, 准教授 (70276921)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
|---|
| Keywords | biodegradable material / PLGA / jaw reconstruction / 顎骨再建 / 骨誘導因子 / 吸収性メッシュプレート / 骨芽細胞 / ドラックデリバリー / 生体吸収性材料 |
|---|
| Outline of Final Research Achievements |
The purpose of this study was to invent biodegradable bone inductive material for jaw reconstruction.
PLGA was used as a base material and osteogenic supplements were incorporated into PLGA（OS/PLGA）. OS/PLGA flagments were immersed in PBS and removed after 24h, 48h, 72h, 96h, 120h, and 144h for analysis. OS were detected untill 144h.
|
