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Changes in peri implant tissue and microcirculation after photo functionalization

Research Project

Project/Area Number 25463058
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Dental engineering/Regenerative dentistry
Research InstitutionKanagawa Dental College

Principal Investigator

MATSUO MASATO  神奈川歯科大学, 大学院歯学研究科, 教授 (30190416)

Co-Investigator(Kenkyū-buntansha) 星 憲幸  神奈川歯科大学, 大学院歯学研究科, 講師 (20339782)
高橋 俊介  神奈川歯科大学, 大学院歯学研究科, 准教授 (60206810)
Co-Investigator(Renkei-kenkyūsha) TAKAHASHI Shunsuke  神奈川歯科大学, 大学院歯学研究科, 教授 (60206810)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords歯周組織 / インプラント / 微小循環 / SEM / インプラント周囲炎 / オッセオインテグレーション / 光機能化処理 / 表面構造 / 光機能化 / 血管鋳型法 / LDF / 光機能化処理処理
Outline of Final Research Achievements

Ultraviolet photo functionalization is a new method for improving the surface characteristics of titanium implants. The purpose of this study was to examine the effect of photo functionalization on morphological analysis. The implant on one side was photo functionalized with UV light (UV group). The implant on the other side was served as the control group (control group). Resin cast specimens were examined by SEM.
In the control group, peri-implant bone was not observed clearly along the implant surface. Instead of bone, In the photo functionalization group, peri-implant bone was thicker than the control group. Blood vessels were buried under newly formed bone tissue. Bone trabeculae are attached to the thick peri-implant bone.The photo functionalization of implants using the photocatalytic activity of titanium improved the bone-binding strength of implants.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (24 results)

All 2017 2016 2015 2014 2013

All Journal Article (7 results) (of which Peer Reviewed: 3 results,  Open Access: 4 results,  Acknowledgement Compliant: 2 results) Presentation (17 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results)

  • [Journal Article] 歯科臨床のためのOral Biology① 歯周組織と歯周疾患2017

    • Author(s)
      松尾雅斗、三辺正人
    • Journal Title

      歯界展望

      Volume: 129 Pages: 272-280

    • Related Report
      2016 Annual Research Report
    • Open Access
  • [Journal Article] 歯科臨床のためのOral Biology② 歯周組織再生療法12017

    • Author(s)
      松尾雅斗、中村社綱
    • Journal Title

      歯界展望

      Volume: 129 Pages: 518-525

    • Related Report
      2016 Annual Research Report
    • Open Access
  • [Journal Article] Microcirculation alterations in experimentally induced gingivitis in dogs.2016

    • Author(s)
      Matsuo M, Okudera T, Takahashi S-S, Wada-Takahashi S, Maeda S, Iimura A.
    • Journal Title

      Anatomical Science International

      Volume: 1 Issue: 1 Pages: 1-6

    • DOI

      10.1007/s12565-015-0324-8

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Numerical Simulation of Alveolar Bone Regeneration and Angiogenesis - Trabecular Bone Formation -2016

    • Author(s)
      Fukuda Y, Nagayama K, Matsuo M
    • Journal Title

      International Conference on Mechanical Engineering

      Volume: - Pages: 13-16

    • NAID

      130007064385

    • Related Report
      2016 Annual Research Report
    • Open Access
  • [Journal Article] 歯槽骨再生と血管新生の数値シミュレーション2016

    • Author(s)
      福田 圭寿,永山 勝也, 松尾 雅斗
    • Journal Title

      日本機械学会 2016 年度年次大会講演論文集

      Volume: 16

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Effect of Ultraviolet Irradiation of the Implant Surface on Progression of Peri-implantitis – A Pilot study in Dogs2015

    • Author(s)
      Ishii K, Matsuo M, Hoshi N, Takahashi SS, Kawamata R, Kimoto K.
    • Journal Title

      Implant Dentistly

      Volume: 25 Issue: 1 Pages: 47-53

    • DOI

      10.1097/id.0000000000000332

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Osseointegration of hydroxyapatite - coated implants with new bone in one stage sinus floor elevation without bone substitute -A long-term animal experiment using canine frontal sinuses-2015

    • Author(s)
      Fukuoka Y C, Watanabe T, Matsuo M, Iimura A, Okudera T.
    • Journal Title

      Journal of Bio-integration

      Volume: 5 Pages: 109-117

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] 光機能化処理によるインプラント周囲炎抑制の試み2016

    • Author(s)
      山本麗子, 東雅啓, 星憲幸, 木本克彦, 松尾雅斗
    • Organizer
      ,第46回日本口腔インプラント学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 口蓋微小循環の形態と機能2016

    • Author(s)
      松尾 雅斗,髙橋 俊介,浜田 信城
    • Organizer
      第58回歯科基礎医学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2016-08-24
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Photo-functionalization(光機能化)によるインプラント周囲骨吸収抑制の試み2016

    • Author(s)
      山本麗子、東雅啓、小笠原敬太、星憲幸、木本克彦、松尾雅斗
    • Organizer
      神奈川歯科大学総会
    • Place of Presentation
      横須賀
    • Related Report
      2016 Annual Research Report
  • [Presentation] 光機能化処理によるインプラント周囲骨形成と微小循環について.2015

    • Author(s)
      松尾雅斗, 奥寺俊允, 星憲幸, 木本克彦
    • Organizer
      神奈川歯科大学総会
    • Place of Presentation
      横須賀
    • Year and Date
      2015-12-05
    • Related Report
      2015 Research-status Report
  • [Presentation] Morphological changes of peri-implant tissue and microvasculature after photo functionalization. Europian association for osseointegration2015

    • Author(s)
      Matsuo M, Okudera T, Maeda S, Matsuo S, Takahashi S-S, Hoshi N, Kimoto K
    • Organizer
      Europian association for osseointegration
    • Place of Presentation
      Stockholm
    • Year and Date
      2015-09-26
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Microvasculature and peri-implant tissue changes after photo functionalization.2015

    • Author(s)
      Matsuo M, Okudera T, Maeda S
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-12
    • Related Report
      2015 Research-status Report
  • [Presentation] インプラント周囲組織の微細血管。サテライトシンポジウム 15 「歯周組織の臨床と基礎 ― 脈管系を中心に― 」2015

    • Author(s)
      松尾雅斗
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Changes in peri-implant tissue and microcirculation after photo functionalization.2015

    • Author(s)
      Matsuo M, Kimoto K
    • Organizer
      nternational Association for Dental Research General Session
    • Place of Presentation
      Boston, USA
    • Year and Date
      2015-03-11 – 2015-03-14
    • Related Report
      2014 Research-status Report
  • [Presentation] Changes of peri-implant tissue and vascular structure after photo functionalized implants.2014

    • Author(s)
      Matsuo M, Okudera T, Maeda S, Hoshi N, Kimoto K
    • Organizer
      7th World Congress on Preventive and Regenerative Medicine
    • Place of Presentation
      台北、台湾
    • Year and Date
      2014-11-04 – 2014-11-08
    • Related Report
      2014 Research-status Report
  • [Presentation] 歯周組織における血管・骨再生の数値シミュレーション2014

    • Author(s)
      松尾 雅斗 、永山 勝也
    • Organizer
      第56回歯科基礎医学会総会
    • Place of Presentation
      福岡、日本
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] Microvascular changes and alveolar bone formation after tooth extraction using platelet-rich plasma2014

    • Author(s)
      MATSUO M, OKUDERA T, MAEDA S
    • Organizer
      7th International symposium on Growth Factors.
    • Place of Presentation
      Paris, France
    • Year and Date
      2014-06-11 – 2014-06-15
    • Related Report
      2014 Research-status Report
  • [Presentation] 実験的インプラント周囲炎におけるチタンインプラント光機能化の効果2013

    • Author(s)
      石井康鉉,松尾雅斗,星憲幸,木本克彦
    • Organizer
      第43回口腔インプラント学会学術大会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 光機能化処理におけるインプラント周囲組織変化について2013

    • Author(s)
      髙橋俊介、松尾雅斗、髙橋聡子
    • Organizer
      第55回歯科基礎医学会総会
    • Place of Presentation
      岡山
    • Related Report
      2013 Research-status Report
  • [Presentation] 骨再生と微小循環2013

    • Author(s)
      松尾雅斗
    • Organizer
      第13回バイオメディカルインフォマティクス研究開発センター(BMIRC)研究会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Microvascular changes of periodontal tissue after inflammation using vascular injection method.2013

    • Author(s)
      Matsuo.M, Takahashi.S-S , Takahashi.S, Iimura.A, Matsuo. S
    • Organizer
      Microscopy conference 2013
    • Place of Presentation
      Regensburg, Germany
    • Related Report
      2013 Research-status Report
  • [Presentation] Particle Simulation on alveolar bone regeneration and angiogenesis -Immature Bone Formation-.2013

    • Author(s)
      Nagayama K, Kisu K, Matsuo M
    • Organizer
      BMCE 2013
    • Place of Presentation
      Hongkong
    • Related Report
      2013 Research-status Report
  • [Presentation] 光機能化処理インプラント周囲炎への抑制効果について.2013

    • Author(s)
      石井康鉉, 松尾雅斗, 星憲幸, 木本克彦, 高橋俊介, 高橋聡子, 川股亮太, 櫻井孝
    • Organizer
      神奈川歯科大学学会総会
    • Place of Presentation
      神奈川歯科大学
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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