Development of functional apatite sheet for hyperesthesia treatment
| Project/Area Number |
25463063
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Kinki University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
YAMAMOTO Ei 近畿大学, 生物理工学部, 准教授 (00309270)
YOSHIKAWA Kazushi 大阪歯科大学, 歯学部, 准教授 (30309182)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 生体材料 / セラミックス / 歯学 / 構造・機能材料 / エナメル質修復 / フッ素化アパタイト / 象牙質知覚過敏 / 象牙質透過抑制率 / 知覚過敏症 / アパタイトシート / 象牙質透過抑制 |
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| Outline of Final Research Achievements |
A functional fluoridated hydroxyapatite (FHAp) sheet that promotes dentin fastening and provides acid resistance was developed, and the technology for rapidly and strongly fixing the FHAp sheet onto dentin was established. First, the optimal conditions for fabricating FHAp thin films using pulsed laser deposition (PLD) were determined. Next, it was shown that a resist coating silicon substrate was useful as an isolation substrate for manufacturing FHAp sheets. The FHAp sheets were found to have five-fold greater acid resistance compared with HAp sheets. Furthermore, we established a pasting method that rapidly and strongly fixed the FHAp sheet onto the dentin.
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Report
(4 results)
Research Products
(57 results)
