A study of calcium sensing receptors in odontogenic tumors
| Project/Area Number |
25463088
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
梶岡 俊一 九州大学, 医学研究院, 准教授 (90274472)
|
|---|
| Project Period (FY) |
2013-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 角化嚢胞性歯原性腫瘍由来線維芽細胞 / カルシウム感受性受容体 / BMP-2 / BMP－２ / 歯原性腫瘍 / 線維芽細胞 |
|---|
| Outline of Final Research Achievements |
The Fibroblasts isolated from odontogenic tumors express calcium sensing receptors. However, the precise function of the receptors is obscure. In this study, we showed that the expression of BMP-2 gene and protein was enhanced by calcium concentration dependent manner in the fibroblasts. These results may suggest the new methods for the bone formation by calcium which is cheep and safe.
|
Report
(5 results)
Research Products
(2 results)
