A RCT study of relieving effect of music sedation on psychological stress before entering dental outpatient room - Investigation with heart rate variability analysis-

• Project/Area Number: 25463126
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Hokkaido University
• Principal Investigator: FUJISAWA Toshiaki 北海道大学, 歯学研究科(研究院), 教授 (30190028)
• Co-Investigator(Kenkyū-buntansha): NITTA Yukie 北海道大学, 大学病院, 助教 (00463737) ; SHIMOJI Sinji 北海道大学, 歯学研究科(研究院), 助教 (30431373) ; KAWANAMI Masamitsu 北海道大学, 歯学研究科(研究院), 教授 (10133761)
• Research Collaborator: MIYATA Kazuki ; ODANAKA Hitomi
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 音楽鎮静 / 心拍変動解析 / 歯科治療恐怖症 / 静脈内鎮静法 / 自律神経系 / 交感神経活動 / 座位 / 局所麻酔

Outline of Final Research Achievements

“Study 1”: 86 adult patients, who were scheduled to undergo impacted tooth extraction under intravenous sedation and local anesthesia, were divided into 4 groups due to the presence or absence of fear and music intervention. The effect of preoperative music intervention was evaluated by assessing the low-frequency/high frequency (LF/HF) ratio of heart rate variability (HRV), indicating sympathetic nervous activity (SNA), and a visual analog scale, indicating subjective preoperative anxiety. Music intervention is useful for relieving anxiety in patients with dental fear before entrance to a dental outpatient operating room.
“Study 2”: The study subjects were 22 healthy young volunteers. The effect of music intervention was evaluated by assessing the LF/HF ratio of HRV under position change or local anesthesia. In healthy young adults, SNA decreases significantly in the sitting and supine positions before local anesthesia with music sedation compared with nonmusic sedation.

Research Products

• [Journal Article] 健全な若年成人における局所麻酔時の音楽鎮静 法の効果-心拍変動解析を用いた自律神経機能評価- (2016)
  • Author(s): 小田中 瞳,下地 伸司,竹生 寛恵,大嶌 理紗,菅谷 勉,藤澤 俊明,川浪 雅光
  • Journal Title: 日本歯科保存学雑誌 Volume: 59 Pages: 9-21
  • NAID: 130005129177
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] 若年成人における歯科用局所麻酔時の音楽鎮静法の効 果-心拍変動解析を用いた自律神経機能評価- (2015)
  • Author(s): 小田中 瞳
  • Organizer: 平成 27 年度北海道歯学会秋季学術大会
  • Place of Presentation: 北海道大学歯学部講堂（北海道;札幌市）
  • Year and Date: 2015-11-25
• [Presentation] 健全な若年成人における局所麻酔時の音楽鎮静の効果 心拍変 動解析を用いた自律神経活動による評価 (2015)
  • Author(s): 小田中瞳, 下地伸司, 竹生寛恵, 大嶌理紗, 菅谷勉, 川浪 雅光
  • Organizer: 142 回春季歯科保存学会学術大会
  • Place of Presentation: 北九州国際会議場（福岡;北九州市）
  • Year and Date: 2015-06-25
• [Presentation] Music Sedation for Patients with Dental Anxiety Relieves Psychological Stress (2015)
  • Author(s): K. Miyata, H. Odanaka, Y. Nitta, S. Shimoji, T. Kanehira, M. kawanaimi, T. Fujisawa
  • Organizer: 93rd General Session & Exhibition of the IADR
  • Place of Presentation: Boston(USA)
  • Year and Date: 2015-03-11 – 2015-03-14
• [Presentation] 歯科手術におけるIVS開始前のストレス軽減を目的とした音楽鎮静ー心拍変動解析を用いた有効性の検討ー (2014)
  • Author(s): 宮田一生、新田幸絵、藤澤俊明
  • Organizer: 第42回 日本歯科麻酔学会総会・学術集会
  • Place of Presentation: 日本歯科大学新潟生命歯学部（新潟県新潟市）
  • Year and Date: 2014-10-11 – 2014-10-12
• [Presentation] Music sedation for reduction of stress from hospital visiting to just before starting intravenous sedation-Investigation of effectiveness with heart rate variability- (2014)
  • Author(s): Kazuki Miyata, Yukie Nitta, Toshiaki Fujisawa
  • Organizer: The 7th Annual Meeting of the Federation of Asian Dental Anesthesiology Society
  • Place of Presentation: IVY Hall in the Nippon Dental University School of Life Dentistry at Niigata(Niigata Prefecture, Niigata City)
  • Year and Date: 2014-10-11