Functional modulation of limbic system is involved in the development of Atypical Odontalgia
| Project/Area Number |
25463142
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
Shiiba Shunj 九州歯科大学, 歯学部, 准教授 (20285472)
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| Co-Investigator(Kenkyū-buntansha) |
NUNOMAKI Masahito 九州歯科大学, 歯科侵襲制御学分野, 助教 (10341489)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 非定型歯痛 / 大脳辺縁系 / 負の情動ストレス / 自律神経活動 / 前頭前野 / 心電図RR'間隔 / スペクトル解析 / 高次脳機能障害 / 海馬 / 扁桃体 / 情動ストレス / 自律神経反応 / ストレス防御機構 / 慢性疼痛 / 筋筋膜痛 / 交感神経活動 / 自律神経機能 / R-R'間隔スペクトル解析 |
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| Outline of Final Research Achievements |
The purpose of this study was to define a response of sympathetic nervous activity against an emotional stress in Atypical odontalgia (AO) patients. The subjects were ten Japanese with AO who visited our clinic for pain relief (AO group) . Ten adult volunteers were also set up as a control group. The emotional stress, visual stress which was produced by international affective picture system was loaded. The changes of sympathetic nervous activity were estimated by spectral analysis of heartbeat fluctuation. The spectral components analyzed were low frequency power, high frequency power and L/H． L/H during emotional stress loading was significantly higher in AO group than in control group. There found an acceleration of sympathetic nervous activity induced by an emotional stress deeply involves in manifestation and maintenance of AO.
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Report
(4 results)
Research Products
(6 results)
