| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Outline of Final Research Achievements |
Analyses of saliva specimens collected from healthy mothers and their children revealed that the prevalence rate of amoxicillin-resistant oral streptococci was approximately 5%, while that of clindamycin-resistant oral streptococci was approximately 30%. Other findings revealed resistance to other antibiotics by these strains as well as their possible transmission from mother to child. Thereafter, analyses of obtained oral specimens were performed to investigate the presence of amoxicillin-resistant strains in subjects at risk for infective endocarditis. However, we were unable to collect an adequate number of samples in order to analyze with statistical significance and consider that a large-scale study is necessary to perform this research.
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