| Project/Area Number |
25463212
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Periodontology
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
AOKI AKIRA 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 (30302889)
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| Co-Investigator(Kenkyū-buntansha) |
小林 宏明 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (50396967)
竹内 康雄 東京医科歯科大学, 大学院医歯学総合研究科, 講師 (60396968)
秋月 達也 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (50401378)
水谷 幸嗣 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (60451910)
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| Co-Investigator(Renkei-kenkyūsha) |
Ohshima Mitsuhiro 奥羽大学, 薬学部, 教授 (30194145)
Hiratsuka Koichi 日本大学, 松戸歯学部, 教授 (80246917)
Komaki Motohiro 東京医科歯科大学, 医歯学総合研究科, 准教授 (30401368)
Iwasaki Kengo 東京医科歯科大学, 医歯学総合研究科, 講師 (40401351)
Tsuchida Sachio 千葉大学, 医学部附属病院, 助教 (90410422)
Taniguchi Yoichi 東京医科歯科大学, 医歯学総合研究科, 非常勤講師 (30648093)
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| Research Collaborator |
Schwarz Frank Heinrich Heine University, Department of Oral Surgery, Associate Professor
Sculean Anton University of Bern, Department of Periodontology, Professor
Coluzzi Donald J. University of California, Department of Preventive and Restorative Dental Sciences, Clinical Professor
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | レーザー / LED / 歯周炎 / インプラント周囲炎 / 歯周ポケット / 細胞 / 細菌 / 抜歯窩 / 高繰り返しパルス発振 / 半導体レーザー / 低出力レーザー治療 / 創傷治癒促進 / 上皮化 / マイクロCT / PCNA / 光 / aPDT / 殺菌 |
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| Outline of Final Research Achievements |
The following studies were performed to establish the application of phototherapy using light energy such as lasers and LEDs for the treatment and prevention of periodontitis and peri-implantitis. We developed a novel comprehensive periodontal pocket treatment protocol using Er:YAG laser and evaluated its clinical effectiveness, investigated photobiomodulation effect of the Er:YAG laser, clarified the promotion of wound healing of extraction sockets using a low-level diode laser, and demonstrated the bactericidal effect using a combination of blue LED and red dye (rose bengal).
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