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Establishment of evaluating autonomic activities during dental treatment for the elderly

Research Project

Project/Area Number 25463233
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionHokkaido University

Principal Investigator

Kashiwazaki Haruhiko  北海道大学, 大学病院, 講師 (10344516)

Co-Investigator(Kenkyū-buntansha) KANEHIRA Takashi  北海道大学, 北海道大学病院, 講師 (90194935)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords高齢者歯科 / 高齢者歯科医療 / 生体情報モニタリングシステム / 生体情報 / 栄養 / ストレス / 自律神経活動
Outline of Final Research Achievements

In order to provide safe dental treatment for the elderly, it is important to understand the patients’ systemic condition, particularly circulation dynamics. We developed a novel system for evaluating autonomic activity during dental treatment. In the present study, we investigated the effectiveness of this system for assessing autonomic activity during dental treatment for the elderly. Heartbeat fluctuation in 9 healthy volunteers in their twenties was measured using the monitoring system during the following several phases of therapy. In many subjects, sympathetic nervous activity increased transiently at the beginning of each treatment, whereas blood pressure and arterial oxygen saturation varied only slightly. Our novel system can be used to precisely and promptly evaluate changes in the systemic condition during dental treatment for the elderly. In the future, we plan to develop methods for safer periodontal therapy in elderly and symptomatic persons.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2016 2015 2013

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (1 results) (of which Invited: 1 results)

  • [Journal Article] Reduced-dose methotrexate in combination with tacrolimus was associated with rapid engraftment and recovery from oral mucositis without affecting the incidence of GVHD.2016

    • Author(s)
      Toshihiro Matsukawa, Daigo Hashimoto, Junichi Sugita, Seitarou Nakazawa, Takae Matsushita, Haruhiko Kashiwazaki, Hideki Goto, Masahiro Onozawa, Kaoru Kahata, Katsuya Fujimoto, Tomoyuki Endo, Takeshi Kondo, Satoshi Hashino, Yutaka Yamazaki, Takanori Teshima.
    • Journal Title

      International Journal of Hematology

      Volume: 印刷中

    • NAID

      120006313418

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship between acetaldehyde concentration in mouth air and tongue coating volume.2015

    • Author(s)
      Yokoi A, Maruyama T, Yamanaka R, Ekuni D, Tomofuji T, Kashiwazaki H, Yamazaki Y, Morita M
    • Journal Title

      Journal of Applied Oral Science

      Volume: 23 Issue: 1 Pages: 64-70

    • DOI

      10.1590/1678-775720140223

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 歯 科治療の影響を解析するための心拍変動を用いた自律神経活動モニター システムの開発2013

    • Author(s)
      下地伸司,小田中瞳,宮田一生,菅谷 勉,藤澤俊明,川浪雅光
    • Journal Title

      北海道歯誌

      Volume: 34 Pages: 23-37

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 北海道大学病院のがん診療における口腔管理2015

    • Author(s)
      柏崎晴彦
    • Organizer
      第13回日本臨床腫瘍学会
    • Place of Presentation
      ロイトン札幌(北海道札幌市)
    • Year and Date
      2015-07-18
    • Related Report
      2015 Annual Research Report
    • Invited

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Published: 2014-07-25   Modified: 2019-07-29  

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