| Project/Area Number |
25463237
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATO Takuichi 東北大学, 歯学研究科(研究院), 講師 (10303132)
WASHIO Jumpei 東北大学, 歯学研究科(研究院), 助教 (20400260)
TAKENAKA Shoji 新潟大学, 医歯学系, 助教 (50313549)
OHSHIMA Hayato 新潟大学, 医歯学系, 教授 (70251824)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 細菌叢 / 齲蝕 / バイオフィルム / ＰＣＲ法 / プラーク / マウス / 口腔細菌 / PCＲ法 / プラークバイオフィルム / PCRシークエンス法 / 小児 |
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| Outline of Final Research Achievements |
As an animal model of dental caries, mice have been generally utilized. In this study, dental plaque microbiota of pre- and post-weanling, were analyzed by using molecular biological techniques. Enterococcus, Escherichia, Lactobacillus and Lactococcus were predominant. From the findings of the present study, the bacterial composition of dental plaque microbiota of mice varies markedly from that of humans (in which Streptococcus, Actinomyces and Veillonella are predominant); and this may be due to differences in the daily diet.
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