Multifaceted approach to the analyses of dental plaque biofilm targeting dental caries-associated bacteria, and its application to dental caries prevention
| Project/Area Number |
25463237
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATO Takuichi 東北大学, 歯学研究科(研究院), 講師 (10303132)
WASHIO Jumpei 東北大学, 歯学研究科(研究院), 助教 (20400260)
TAKENAKA Shoji 新潟大学, 医歯学系, 助教 (50313549)
OHSHIMA Hayato 新潟大学, 医歯学系, 教授 (70251824)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 細菌叢 / 齲蝕 / バイオフィルム / ＰＣＲ法 / プラーク / マウス / 口腔細菌 / PCＲ法 / プラークバイオフィルム / PCRシークエンス法 / 小児 |
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| Outline of Final Research Achievements |
As an animal model of dental caries, mice have been generally utilized. In this study, dental plaque microbiota of pre- and post-weanling, were analyzed by using molecular biological techniques. Enterococcus, Escherichia, Lactobacillus and Lactococcus were predominant. From the findings of the present study, the bacterial composition of dental plaque microbiota of mice varies markedly from that of humans (in which Streptococcus, Actinomyces and Veillonella are predominant); and this may be due to differences in the daily diet.
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Report
(4 results)
Research Products
(34 results)
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[Journal Article] <i>Porphyromonas bronchialis</i> sp. nov. Isolated from Intraoperative Bronchial Fluids of a Patient with Non-Small Cell Lung Cancer2015
Author(s)
T. Sato, J. Tomida, T. Naka, N. Fujiwara, A. Hasegawa, Y. Hoshikawa, J. Matsuyama, N. Ishida, T. Kondo, K. Tanaka, N. Takahashi, Y. Kawamura
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Journal Title
The Tohoku Journal of Experimental Medicine
Volume: 237
Issue: 1
Pages: 31-37
DOI
NAID
ISSN
0040-8727, 1349-3329
Related Report
Peer Reviewed / Open Access
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[Journal Article] Porphyromonas pogonae sp. nov., an anaerobic but low concentration oxygen adapted coccobacillus isolated from lizards (Pogona vitticeps) or human clinical specimens, and emended description of the genus Porphyromonas Shah and Collins 19882015
Author(s)
Y. Kawamura, S. Kuwabara, S.A. Kania, H. Kato, M. Hamagishi, N. Fujiwara, T. Sato, J. Tomida, K. Tanaka, D.A. Bemis
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Journal Title
Syst. Appl. Microbiol.
Volume: 38
Issue: 2
Pages: 104-109
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Profiling of microbiota from infected root canals with and without marginal leakage using anaerobic culture and molecular biological techniques (16S rRNA gene sSequencing)2015
Author(s)
Sato T, Yamaki K, Kawamura Y, Tomida J, Tian L, Ishida N, Takeuchi Y, Hashimoto K, Abiko Y, Matsuyama J, Takahashi N
Organizer
The 25th ECCMID
Place of Presentation
Copenhagen, Denmark
Year and Date
2015-04-28
Related Report
Int'l Joint Research
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[Presentation] Porphyromonas pogonae sp. nov., a strong beta-hemolytic, low concentration oxygen tolerant species from lizards and human clinical specimens2014
Author(s)
Kawamura Y, Kuwabara S, Kania SA, Kato H, Hamagishi M, Hayakawa S, Fujiwara N, Naka T, Sato T, Tomida J, Tanaka K, Yoshida Y, Morita Y, Bemis DA
Organizer
The 114th General Meeting of ASM
Place of Presentation
Boston Convention & Exhibition Center, Boston, USA
Year and Date
2014-05-20
Related Report
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[Book] Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface2015
Author(s)
Sato T, Kawamura Y, Yamaki K, Ishida N, Tian L, Takeuchi Y, Hashimoto K, Abiko Y, Mayanagi G, Washio J, Matsuyama J, Takahashi N
Total Pages
6
Publisher
Springer
Related Report
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[Book] Interface Oral Health Science 20142015
Author(s)
Sato T, Kawamura Y, Yamaki K, Ishida N, Tian L, Takeuchi Y, Hashimoto K, Abiko Y, Mayanagi G, Washio J, Matsuyama J, Takahashi N
Publisher
Springer
Related Report
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[Book] Interface Oral Health Science 20142015
Author(s)
Sakashita R, Takami M, Ono H, Nishihira T, Sato T, Hamada M: Preventing aspiration pneumonia for the elderly: a review focused on the impact of the consistency of food substances
Publisher
Springer
Related Report
