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Expression status of semaphorin might be related to the status of periodontal tissue

Research Project

Project/Area Number 25463245
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionHiroshima University

Principal Investigator

Shimazu Atsushi  広島大学, 医歯薬保健学研究院(歯), 助教 (10274094)

Research Collaborator YOSHIMURA Riko  広島大学, 歯学部, 学生
FUJIMOTO Chise  広島大学, 大学院医歯薬保健学研究科, 学生
Takahashi Ayaka  広島大学, 大学院医歯薬保健学研究科, 学生
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordssemaphorin / plexin / 歯髄組織 / 歯周組織 / 歯髄
Outline of Final Research Achievements

Semaphorin (Sema) 3A is known as an inducer of axon outgrowth. In this study, we demonstrated that distribution of Sema 3A in periodontal and dental pulp tissues. We also analyzed of Sema 3A expressing cells and their receptor expressing cells in pulp tissue. These studies suggested that Sema 3A might be involved in the maintenance of tissue homeostasis via its receptor expressing cells.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2016 2015 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Ameloblastin in Hertwig's epithelial root sheath regulates tooth root formation and development.2013

    • Author(s)
      Hirose N., Shimazu A., Watanabe M., Tanimoto K., Koyota S., Sugiyama T., Uchida T., Tanne K.
    • Journal Title

      PLoS One

      Volume: 8(1)

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Relationship between oral health status and behavior in the birth order of the school children.2016

    • Author(s)
      Shimazu A., Nosou M., Fukada E., Nishimura R., Sugiyama M.
    • Organizer
      12th Asian Academy of Preventive Dentistry
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-05-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マウス歯周および歯髄組織における Semaphorin 3A の発現と 機能について2015

    • Author(s)
      藤本千晴, 吉村理湖, 島津 篤, 杉山 勝
    • Organizer
      第24回近畿・ 中国・ 四国口腔衛生学会
    • Place of Presentation
      山口
    • Year and Date
      2015-09-27
    • Related Report
      2015 Research-status Report
  • [Presentation] Study of the expression of Semaphorin 3A in mouse pulp tissue.2015

    • Author(s)
      Riko Yoshimura, Chise Fujimoto, Atsushi Shimazu, Takashi Uchida, Hiroki Nikawa, Masaru Sugiyama
    • Organizer
      88th Annual Meeting of Japanese Tissue Culture Association
    • Place of Presentation
      Hiroshima
    • Year and Date
      2015-05-26
    • Related Report
      2015 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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