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Elucidation of eating behavior-related disorders of dementia patients by the mirror neurons

Research Project

Project/Area Number 25463282
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionNational Center for Geriatrics and Gerontology

Principal Investigator

Watanabe Yutaka  国立研究開発法人国立長寿医療研究センター, 口腔疾患研究部, 室長 (30297361)

Research Collaborator SUMA Sino  国立研究開発法人国立長寿医療研究センター, 口腔疾患研究部, 流動研究員 (70759365)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords認知症 / 食行動関連障害 / ミラーニューロン / 孤食 / 食欲 / 軽度認知障害 / ミラーニューロンシステム / 栄養状態
Outline of Final Research Achievements

The purpose of this study is to examine the factor to eating behavior-related disorders associated with dementia. Therefore, we have investigated the factors that related to eating alone and the eating behavior-related disorder in 2522 patients who are attending dementia disease center. At first, we analyzed factors that related to the loss of appetite for eating behavior-related disorders according to disease type of dementia. Secondly, we investigated the anatomic change of the brain, the mirror neuron and the brain function associated with cognitive function of the people with mild cognitive impairment by various brain function measurement devices. In addition, the program that limit the eating alone and activate the mirror neuron system on the swallowing movement to the people with mild cognitive impairment, was investigated for the possibility of suppressing the eating behavior-related disorders.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (45 results)

All 2016 2015 2014 2013 Other

All Journal Article (15 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 14 results,  Open Access: 8 results) Presentation (23 results) (of which Int'l Joint Research: 12 results) Book (7 results)

  • [Journal Article] The need and availability of dental services for terminally ill cancer patients: a nationwide survey in Japan.2016

    • Author(s)
      Ohno T, Morita T, Tamura F, Hirano H, Watanabe Y, Kikutani T.
    • Journal Title

      Support Care Cancer.

      Volume: 24 Issue: 1 Pages: 19-22

    • DOI

      10.1007/s00520-015-2734-5

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between Skeletal Muscle Mass and Swallowing Function in Patients with Alzheimer’s Disease.2016

    • Author(s)
      Takagi D, Hirano H, Watanabe Y, Edahiro A, Ohara Y, Yoshida H, Kim H, Murakami K, Hironaka S.
    • Journal Title

      Geriatr Gerontol Int.

      Volume: -

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sarcopenia: Prevalence and associated factors based on different suggested definitions in community-dwelling older adults.2016

    • Author(s)
      Kim H, Hirano H, Edahiro A, Ohara Y, Watanabe Y, Kojima N, Kim M, Hosoi E,Yoshida Y, Yoshida H, Shinkai S.
    • Journal Title

      Geriatr Gerontol Int.

      Volume: 16 Issue: S1 Pages: 110-22

    • DOI

      10.1111/ggi.12723

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship between swallowing function and the skeletal muscle mass of older adults requiring long-term care2015

    • Author(s)
      Murakami K, Hirano H, Watanabe Y, Edahiro A, Ohara Y, YOSHIDA H, Kim H, Takagi D, Hironaka S.
    • Journal Title

      Geriatrics & Gerontology International

      Volume: 15 Issue: 10 Pages: 1185-1192

    • DOI

      10.1111/ggi.12572

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An examination of factors related to aspiration and silent aspiration in older adults requiring long-term care in rural Japan2015

    • Author(s)
      Sakai K, Hirano H, Watanabe Y, Tohara H, Sato E, Sato K, Katakura A
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 43 Issue: 2 Pages: 103-110

    • DOI

      10.1111/joor.12349

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Factors associated with older adults' need for oral hygiene management by dental professionals2015

    • Author(s)
      Morishita S, Watanabe Y, Ohara Y, Edahiro A, Sato E, Suga T, Hirano H.
    • Journal Title

      Geriatrics & Gerontology International

      Volume: - Issue: 8 Pages: 1-7

    • DOI

      10.1111/ggi.12585

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 認知症グループホーム入居高齢者における認知症重症度と口腔機能および栄養状態の関連2015

    • Author(s)
      小原由紀, 高城大輔, 枝広あや子, 森下志穂, 渡邊 裕,平野浩彦
    • Journal Title

      日衛学誌

      Volume: 9 Pages: 69-79

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] オーラル・フレイルとは2015

    • Author(s)
      渡邊 裕
    • Journal Title

      臨床栄養

      Volume: 127 Pages: 742-743

    • Related Report
      2015 Annual Research Report
  • [Journal Article] How masticatory function and periodontal disease relate to senile dementia.2015

    • Author(s)
      Watanabe Y, Hirano H, Matsushita K.
    • Journal Title

      Japanese Dental Science Review

      Volume: 51 Issue: 1 Pages: 34-40

    • DOI

      10.1016/j.jdsr.2014.09.002

    • NAID

      50009645832

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The relationship between chewing ability and sarcopenia in Japanese community-dwelling elderly subjects.2014

    • Author(s)
      Murakami M, Hirano H, Watanabe Y, Sakai K, Katakura A.
    • Journal Title

      Geriatrics and Gerontology International

      Volume: - Issue: 8 Pages: 1007-12

    • DOI

      10.1111/ggi.12399

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Factors associated with self-rated oral health among community-dwelling older Japanese: A cross-sectional study.2014

    • Author(s)
      Ohara Y, Hirano H, Watanabe Y, Obuchi S, Yoshida H, Fujiwara Y, Ihara K, Kawai H, Mataki S.
    • Journal Title

      Geriatrics and Gerontology International

      Volume: - Issue: 6 Pages: 755-61

    • DOI

      10.1111/ggi.12345

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mirror neurons activated during swallowing and finger movements: An fMRI study2014

    • Author(s)
      Ogura M, Watanabe Y, Sanjo Y, Edahiro A, Sato K, Katakura A
    • Journal Title

      J Oral Maxillofac Surg Med Pathol.

      Volume: 26 Issue: 2 Pages: 95-102

    • DOI

      10.1016/j.ajoms.2013.08.008

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Mirror neurons activated during swallowing and finger movements: An fMRI study2014

    • Author(s)
      Ogura M, Watanabe Y, Sanjo Y, Edahiro A, Sato K, Katakura A
    • Journal Title

      J Oral Maxillofac Surg Med Pathol

      Volume: 26 Pages: 188-197

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Detecting signs of dysphagia in patients with Alzheimer's disease with oral feeding in daily life.2013

    • Author(s)
      Sato E, Hirano H, Watanabe Y, Edahiro A, Sato K, Yamane G, Katakura A.
    • Journal Title

      Geriatr Gerontol Int

      Volume: - Issue: 3 Pages: 549-55

    • DOI

      10.1111/ggi.12131

    • Related Report
      2014 Research-status Report 2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] アルツハイマー病と血管性認知症高齢者の食行動の比較に関する調査報告: 第一報食行動変化について‐2013

    • Author(s)
      枝広あや子,平野浩彦,山田律子,千葉由美,渡邊 裕
    • Journal Title

      日本老年医学会雑誌

      Volume: 50(5) Pages: 651-660

    • NAID

      130004917116

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 認知症患者の食欲に影響を与える要因の検討2016

    • Author(s)
      須磨紫乃、渡邊 裕、松下健二、荒井秀典、櫻井 孝
    • Organizer
      第26回日本疫学会学術総会
    • Place of Presentation
      米子
    • Year and Date
      2016-01-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The relationship between frailty and oral function in community-dwelling elderly people2015

    • Author(s)
      Watanabe Y., Morishita S., Suma S., Edahiro A., Hirano H.o, Motokawa K., Ohara Y., Arai H., Suzuki T.
    • Organizer
      International Association of Gerontology and Geriatrics 2015
    • Place of Presentation
      Chiang Mai
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of the comprehensive oral care program on oral function and frailty in community-dwelling older adults2015

    • Author(s)
      Suma S., Watanabe Y., Morishita S., Edahiro A., Hirano H., Motokawa K., Hironaka S., Takagi D., Ohara Y., Arai H., Suzuki T.
    • Organizer
      International Association of Gerontology and Geriatrics 2015
    • Place of Presentation
      Chiang Mai
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between sarcopenia and chewing ability in japanese community-dwelling elderly–is Sarcopenia a contributing factor for decline in chewing ability2015

    • Author(s)
      Hirano H., Watanabe Y., Edahiro A., Kawai H., Kim H., Yoshida H., Obuchi S.
    • Organizer
      International Association of Gerontology and Geriatrics 2015
    • Place of Presentation
      Chiang Mai
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A statement of position for oral health management for the elderly peoples with dementia from The Japanese Society of Gerodontology(JSG)2015

    • Author(s)
      Edahiro A., Hirano H., Watanabe Y., Ichikawa T., Sakurai K.
    • Organizer
      International Association of Gerontology and Geriatrics 2015
    • Place of Presentation
      Chiang Mai
    • Year and Date
      2015-10-21
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between Nutritional Status and Severity of Dementia in Group Homes for Dementia2015

    • Author(s)
      Motokawa K., Edahiro A., Hirano H., Watanabe Y., Hironaka S., Takagi D.
    • Organizer
      International Association of Gerontology and Geriatrics 2015
    • Place of Presentation
      Chiang Mai
    • Year and Date
      2015-10-21
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Meal care for eating dysfunction in Alzheimer’s disease, relationship with declines of attention and consciousness2015

    • Author(s)
      Edahiro A., Hirano H., Watanabe Y., Hironaka S., Takagi D., Awata S.
    • Organizer
      International Association of Gerontology and Geriatrics 2015
    • Place of Presentation
      Chiang Mai
    • Year and Date
      2015-10-21
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Nutrition of elderly person with Alzheimer’s disease, related with eating dysfunction; examination on the basis of functional assessment staging (FAST)2015

    • Author(s)
      Edahiro A., Hirano H., Motokawa K., Watanabe Y.
    • Organizer
      The 16th Parenteral and Enteral Nutrition Society of Asia 2015
    • Place of Presentation
      Nagoya
    • Year and Date
      2015-07-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between severity of dementia and nutritional status among older people with dementia in group homes2015

    • Author(s)
      Motokawa K., Hirano H., Edahiro A., Watanabe Y.
    • Organizer
      The 16th Parenteral and Enteral Nutrition Society of Asia 2015
    • Place of Presentation
      Nagoya
    • Year and Date
      2015-07-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Risk factors for appendicular skeletal muscle mass decline in elderly people with Alzheimer’s Disease2015

    • Author(s)
      Watanabe Y., Hirano H., Edahiro A., Ohara Y., Takagi D., Murakami K., Hironaka S.
    • Organizer
      The 30th International Conference of Alzheimer’s Disease International
    • Place of Presentation
      Perth
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Transitions of Eating and Swallowing Function Accompanying Dementia Progression - Examination on The Basis Of Functional Assessment Staging (FAST)2015

    • Author(s)
      Edahiro A., Hirao H., Watanabe Y., Ohara. Y.
    • Organizer
      The 30th International Conference of Alzheimer’s Disease International
    • Place of Presentation
      Perth
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between nutritional status and severity of Alzheimer's disease2015

    • Author(s)
      Motohashi Y., Hirano H., Watanabe Y., Edahiro A., Ohara Y., Takagi D., Hironaka S.
    • Organizer
      The 30th International Conference of Alzheimer’s Disease International
    • Place of Presentation
      Perth
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 当院の認知症患者における拒食に対する介入例2015

    • Author(s)
      木下かほり、朝倉三恵子、小出由美子、間瀬広樹、金子康彦、渡邊 裕、佐竹昭介、山岡朗子
    • Organizer
      第30回日本静脈経腸栄養学会学術集会
    • Place of Presentation
      兵庫
    • Year and Date
      2015-02-11
    • Related Report
      2014 Research-status Report
  • [Presentation] 認知症重度化にともなう摂食嚥下機能の変化―Functional Assessment Staging(FAST)を基準に―2014

    • Author(s)
      枝広あや子、平野浩彦、小原由紀、渡邊 裕、森下志穂、高城大輔
    • Organizer
      第20回日本摂食嚥下リハビリテーション学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-26
    • Related Report
      2014 Research-status Report
  • [Presentation] 認知症重症度と摂食嚥下機能・栄養状態との関連について―Clinical Dementia Rating(CDR)を基準とした検討―2014

    • Author(s)
      高城大輔、平野浩彦、枝広あや子、小原由紀、渡邊 裕、森下志穂、村上浩史、弘中祥司
    • Organizer
      第20回日本摂食嚥下リハビリテーション学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-26
    • Related Report
      2014 Research-status Report
  • [Presentation] 高齢者ブレインバンクでのレビー小体型認知症診断症例における摂食嚥下障害の状況について(第一報)2014

    • Author(s)
      本橋佳子、渡邊裕、木村絵美子、平野浩彦、枝広あや子
    • Organizer
      日本老年歯科医学会第25回学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-06-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 認知症重度化にともなう口腔関連機能の変遷―Functional Assessment Staging(FAST)を基準にした検討―2014

    • Author(s)
      枝広あや子、平野浩彦、小原由紀、渡邊裕、森下志穂、村上正治、高城大輔
    • Organizer
      日本老年歯科医学会第25回学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-06-13
    • Related Report
      2014 Research-status Report
  • [Presentation] アルツハイマー型認知症高齢者の摂食嚥下機能と栄養状態に関する報告2014

    • Author(s)
      高城大輔、平野浩彦、渡邊裕、枝広あや子、小原由紀、森下志穂、大堀嘉子
    • Organizer
      日本老年歯科医学会第25回学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-06-13
    • Related Report
      2014 Research-status Report
  • [Presentation] A SURVEY OF ORAL AND SWALLOWING FUNCTIONS FOCUSING ON SILENT ASPIRATION AMONG DEMENTIA ELDERLY CLIENTS

    • Author(s)
      Hirohiko HIRANO, Emiko SATO, Yutaka WATANABE, Ayako EDAHIRO, Yuki OHARA, Shiho MORISHITA, Haruka TOHARA and Yumi CHIBA
    • Organizer
      The20th IAGG World Congress of Gerontology and Geriatrics June
    • Place of Presentation
      Seoul , Korea
    • Related Report
      2013 Research-status Report
  • [Presentation] A SURVEY OF THE FACTOR ABOUT ORAL HYGIENE MANAGEMENT IN THE DEPENDENT ELDERLY ~ FINDDINGS ON INVENTORY SURVEY IN SPECIFIC REGION

    • Author(s)
      Shiho MORISHITA, Yutaka WATANABE, Hirohiko HIRANO, Yuki OHARA, Emiko SATO, Ayako EDAHIRO, Takeo SUGA, and Takao SUZUKI
    • Organizer
      The20th IAGG World Congress of Gerontology and Geriatrics
    • Place of Presentation
      Seoul , Korea
    • Related Report
      2013 Research-status Report
  • [Presentation] RELATIONSHIP BETWEEN FUNCTIONAL DEFICT OF OLFACTORY AND FEEDING OF ELDERLY PEOPLE WITH DEMENTIA – ESPECIALLY WITH CONCERNS TO ALZHEIMER’S DESEASE?

    • Author(s)
      Yutaka WATANABE, Shiho MORISHITA, Emiko SATO, Hirohiko HIRANO, Ayako EDAHIRO, Haruka TOHARA, Yuki OHARA, and Takao SUZUKI
    • Organizer
      The20th IAGG World Congress of Gerontology and Geriatrics June 25 2013
    • Place of Presentation
      Seoul , Korea
    • Related Report
      2013 Research-status Report
  • [Presentation] 特別養護老人ホームの入所者に対する「高齢者のための自立摂食維持マニュアル」の効果について

    • Author(s)
      渡邊 裕、森下志穂、平野浩彦、枝広あや子、小原由紀、田中弥生、池山豊子
    • Organizer
      第28回日本老年学会総会
    • Place of Presentation
      大阪
    • Related Report
      2013 Research-status Report
  • [Presentation] 要介護高齢者における摂食・嚥下障害に関連する因子の検討

    • Author(s)
      酒井克彦、平野浩彦、渡邊 裕、菅 武雄、枝広あや子、佐藤絵美子、村上正治、吉田雅康、森下志穂、小原由紀、片倉 朗
    • Organizer
      第28回日本老年学会総会
    • Place of Presentation
      大阪
    • Related Report
      2013 Research-status Report
  • [Book] 口腔内科学2016

    • Author(s)
      渡邊 裕
    • Publisher
      永末書店
    • Related Report
      2015 Annual Research Report
  • [Book] 完全版介護予防マニュアル2015

    • Author(s)
      渡邊 裕
    • Publisher
      法研
    • Related Report
      2015 Annual Research Report
  • [Book] 老年歯科医学2015

    • Author(s)
      渡邊 裕
    • Publisher
      医歯薬出版
    • Related Report
      2015 Annual Research Report
  • [Book] In Reference Module in Biomedical Sciences2014

    • Author(s)
      Watanabe Y
    • Publisher
      Elsevier
    • Related Report
      2014 Research-status Report
  • [Book] 基礎から学ぶ口腔ケア 第2版2013

    • Author(s)
      渡邊 裕
    • Total Pages
      159
    • Publisher
      Gakken
    • Related Report
      2013 Research-status Report
  • [Book] 口腔ケアの疑問解決Q&A2013

    • Author(s)
      渡邊 裕
    • Total Pages
      183
    • Publisher
      Gakken
    • Related Report
      2013 Research-status Report
  • [Book] 口腔の緩和医療・緩和ケア2013

    • Author(s)
      渡邊 裕
    • Total Pages
      220
    • Publisher
      永末書店
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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