Promoted Nursing Care of Wound Healing Based on Mechanisms of The Deep Tissue Injury (DTI)
Project/Area Number |
25463287
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Fundamental nursing
|
Research Institution | Yamagata University |
Principal Investigator |
MATSUDA YUMI 山形大学, 医学部, 准教授 (90444926)
|
Co-Investigator(Kenkyū-buntansha) |
KANNO EMI 東北大学, 大学院医学系研究科, 講師 (10431595)
ISHIDA YOKO 山形大学, 医学部看護学科, 講師 (60322335)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 深部損傷褥瘡 / DTI / 冷罨法 / 温罨法 / 創傷治癒 / HMGB1 / 線維芽細胞 / deep tissue Injury / 皮膚 / 深部損傷褥瘡(DTI) / 圧迫創動物モデル / 褥瘡発生初期 / 看護ケア |
Outline of Final Research Achievements |
In the present study, we evaluated the effects that cool and hot packs as an initial therapy has contributed wound healing on post-pressure induced deep tissue injury model mouse. Wound healing is similar to that of secondary intention on the model mouse. The cool group had significant tissue necrosis in the epidermis/dermis, but l though the deep skeletal muscle had been damaged, muscle cell regeneration was noted on days 5 to 7. The hot group exhibited reverse findings in the respective tissue layers, and had delayed regeneration of skeletal muscle. Applied cool or hot packs to the pressure wound were indicated different effects on each layer of the skin tissue including muscles.
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Report
(4 results)
Research Products
(8 results)