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Empirical Research on the Damage to Skin and Blood Vessels from Anticancer Drugs, as Drawn Attention to by Nursing Staff Engaged in Cancer Chemotherapy

Research Project

Project/Area Number 25463311
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Fundamental nursing
Research InstitutionTohoku Fukushi University (2015)
Iwate Prefectural University (2013-2014)

Principal Investigator

oikawa masahiro  東北福祉大学, 健康科学部, 講師 (60537009)

Co-Investigator(Kenkyū-buntansha) Takeda Toshiaki  岩手県立大学, 看護学部, 教授 (40305248)
Hirano Akihiko  岩手県立大学, 看護学部, 准教授 (30305255)
Miura Natsuko  岩手県立大学, 看護学部, 講師 (40347191)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords抗がん剤 / ステロイド / 血管外漏出 / 罨法 / ロゼウス
Outline of Final Research Achievements

Nursing staff have voiced their doubts about the actual effectiveness of local steroid injections as a treatment for events of extravasation of anticancer drugs. In this study, we have taken up this issue noticed by the nursing staff, and examined the effects of local steroids. We determined that only Rozeus displayed some effect, but were unable to obtain a clear result as to its effectiveness. In addition, we performed some non-invasive observations of internal skin tissue after extravasation events, employing thermography and cutaneous ultrasound. Particularly cutaneous ultrasounds appeared to be effective for observing deeper cutaneous tissue unobservable with the naked eye.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (8 results)

All 2015 2014 2013 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (6 results) Remarks (1 results)

  • [Journal Article] 点滴漏れ時の院内ケアマニュアルの使用経験2014

    • Author(s)
      葛西英子、荒井悦子、及川正広、三浦奈都子、武田敏明
    • Journal Title

      日本看護技術学会誌

      Volume: 13 Pages: 230-236

    • NAID

      130005155581

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] 抗がん剤血管外漏出に対するステロイド剤局所作用の検討2015

    • Author(s)
      及川正広
    • Organizer
      第29回日本がん看護学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2015-02-28 – 2015-03-01
    • Related Report
      2014 Research-status Report
  • [Presentation] ドキソルビシンの血管外漏出性皮膚傷害に対する効果的な罨法法の検討2014

    • Author(s)
      三浦奈都子
    • Organizer
      第44回日本創傷治癒学会学術集会
    • Place of Presentation
      メトロポリタン仙台(宮城県)
    • Year and Date
      2014-12-02 – 2014-12-03
    • Related Report
      2014 Research-status Report
  • [Presentation] 起壊死性抗がん剤の血管外漏出性皮膚傷害に対する非侵襲的観察法の検討2014

    • Author(s)
      及川正広
    • Organizer
      第2回看護理工学会学術集会
    • Place of Presentation
      大阪大学豊中キャンパス大学会館(大阪府)
    • Year and Date
      2014-10-04 – 2014-10-05
    • Related Report
      2014 Research-status Report
  • [Presentation] 抗がん剤漏出時における皮膚傷害に対するステロイド剤局所作用の検討2014

    • Author(s)
      及川正広
    • Organizer
      日本看護研究学会第40回学術集会
    • Place of Presentation
      奈良県文化会館
    • Related Report
      2013 Research-status Report
  • [Presentation] ビンカアルカロイド系抗がん剤の血管外漏出に対する罨法の作用2013

    • Author(s)
      及川正広
    • Organizer
      第33回日本看護化学学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Related Report
      2013 Research-status Report
  • [Presentation] 抗がん剤血管外漏出に対する非侵襲的観察法に関する検討

    • Author(s)
      及川正広
    • Organizer
      第1回看護理工学会学術集会
    • Place of Presentation
      東京大学本郷キャンパス
    • Related Report
      2013 Research-status Report
  • [Remarks] 岩手県立大学看護学部エビデンスベース看護情報センター

    • URL

      http://ebn.nurs.iwate-pu.ac.jp/ebn/

    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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