| Project/Area Number |
25515006
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
睡眠科学
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
OZONE MOTOHIRO 東京慈恵会医科大学, 医学部, 准教授 (50246386)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | Cognitive therapy / insomnia / instability of sleep / 原発性不眠 / CAP / 認知行動療法 / 不眠 / 睡眠ポリグラフ検査 / 自律神経活動 |
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| Outline of Final Research Achievements |
Lately, it is reported that overdosing hypnotics is an issue on the treatment of insomnia. Cognitive-Behavioral Therapy for insomnia(CBTi) has been used for insomniac overseas, instead of pharmacological therapy. However, the therapeutic effects have not been revealed objectively by means of the electroencephalography.
17 Japanese patients with insomnia participated in this study and were administered CBTi. The changes in encephalogram during sleep were evaluated after CBTi using the Cyclic Alternating Pattern method, which is able to measure the instability of sleep. As the result, it was high in the instability of sleep of patients with insomnia, compared with normal level. Furthermore, it was found that the more instability of sleep in baseline, the more effective to CBTi. In addition, the therapeutic effect of CBTi appeared approximately three months after CBTi.
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