Detection of translational signal in RNAs
| Project/Area Number |
25540129
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Life / Health / Medical informatics
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| Research Institution | Tohoku University |
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Principal Investigator |
YAMASHITA Riu 東北大学, 東北メディカル・メガバンク機構, 准教授 (10401259)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 翻訳制御 / non-coding RNA / データベース / 翻訳調節 / short peptide / 翻訳 / Ribosomal profiling / モチーフ / 国際情報交換 |
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| Outline of Final Research Achievements |
There is not clear definition of non-coding RNAs so far. Here I detected potential coding RNA from non-coding RNAs. Some of them were detected as short peptides by Mass spectrometry analysis. Moreover, one of them shows cell-cycle accelation by overexpression of the smll peptide. I made the databse for potetial small peptide, and it is availble on web site.
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Report
(3 results)
Research Products
(9 results)
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[Journal Article] MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors.2013
Author(s)
Okuyama K, Ikawa T, Gentner B, Hozumi K, Harnprasopwat R, Lu J, Yamashita R, Ha D, Toyoshima T, Chanda B, Kawamata T, Yokoyama K, Wang S, Ando K, Lodish HF, Tojo A, Kawamoto H, Kotani A
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Journal Title
Proc Natl Acad Sci U S A.
Volume: 110
Issue: 33
Pages: 13410-13415
DOI
Related Report
Peer Reviewed
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