| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Cell migration is known to play an important role in a number of physiological events in living body such as morphogenesis, wound healing, and tumor metastasis. It is therefore important to study the mechanism of cell migration from the viewpoint of mechanics. The objective of this study is to newly design and fabricate a multichannel device integrated with micropillar technology to evaluate cell traction forces during cell migration. The multichannel device has been successfully fabricated, which allows to modulate cell migration rate by changing the stiffness of micropillars and by giving the micropillars anisotropic properties.
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