| Project/Area Number |
25560238
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Medical systems
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
AKAHOSHI Tomohiko 九州大学, 医学研究院, 講師 (20336019)
MURATA Masaharu 九州大学, 先端融合医療レドックスナビ研究拠点, 准教授 (30304744)
HASHIZUME Makoto 九州大学, 医学研究院, 教授 (90198664)
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| Co-Investigator(Renkei-kenkyūsha) |
KUMASHIRO Ryuichi 九州大学, 大学病院, 医員 (10631591)
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| Project Period (FY) |
2013-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Keywords | 画像診断システム / 分光学的解析 / 人間医工学 / 医用システム / 疑似的病理検査 / ハイパースペクトルカメラ / 質量分析 |
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| Research Abstract |
We examined a possibility of our developed hyper spectral camera system for a diagnosis of colorectal cancer. During the endoscopic screening, hyper spectral camera by which the reflectance spectral data of 400-800nm for 640x480 pixels are captured. All lesions that appeared abnormal and normal mucosa around the lesion were targeted. Resected specimens of primary colorectal cancer and non-neoplastic mucosa were obtained and measured spectrum at several points of the colorectal mucosa. We evaluated accuracy of the ability for tumor detection by the hyper spectral camera system. The average reflection intensity rate of each categories are, normal mucosa; 0.96, hyperplastic polyp; 0.90, adenoma; 0.86 and adenocarcinoma; 0.60. The increased spectral absorption ex vivo at 510nm was observed. Tumor and non-tumor tissue could be discriminated with a sensitivity of 62-75% and a specificity of 83-85% in both in vivo and ex vivo experiment.
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