| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
Brain glycogen could be utilized during prolonged exhaustive exercise. However, the role of brain glycogen in exercise endurance is unclear. To address this issue, we examined the effect of inhibition of brain glycogenolysis on exercise endurance. Blockade of brain glycogenolysis and lactate transport during exercise decreased endurance capacity associated with brain ATP levels. Our results demonstrated that lactate from brain glycogen fuels the exercising brain to retain exercise endurance, providing a new understanding of brain energetics during exercise.
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