Visualization of mitochondrial behavior for oxygen environment in myocytes

Research Project

Project/Area Number	25560335
Research Category	Grant-in-Aid for Challenging Exploratory Research
Allocation Type	Multi-year Fund
Research Field	Sports science
Research Institution	The University of Electro-Communications
Principal Investigator	KANO Yutaka 電気通信大学, 情報理工学(系)研究科, 教授 (90293133)
Project Period (FY)	2013-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000) Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	バイオイメージング / 骨格筋 / in vivo / ミトコンドリア / 酸素
Outline of Final Research Achievements	The purpose of this study was construction of in vivo bio-imaging model to examine the relationship between intracellular oxygen level and mitochondrial behavior. This study focused on the possibility that the mitochondria move to capillary around for oxygen uptake at hypoxia.In this study, we were not able to build it about the mitochondrial labelling using the fluorescence protein to evaluate mitochondrial movement although a mitochondrial imaging under the in vivo environment was successful.