The effects of environmental stresses of high-altitude (i.e., hypoxia and hypothermia) on activation of brown adipose tissue and anti-obesity.
| Project/Area Number |
25560380
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
松生 香里 東北大学, 医学系研究科, 助教 (60513570)
橋本 健志 立命館大学, スポーツ健康科学部, 准教授 (70511608)
山内 潤一郎 首都大学東京, 人間健康科学研究科, 准教授 (70552321)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 高所 / 低酸素 / 脂質代謝 / 脂肪蓄積 / 肥満 / 代謝特性 / 形態特性 / 運動 / 高所環境 / 低温 / 褐色脂肪 / 白色脂肪 / 褐色脂肪細胞 |
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| Outline of Final Research Achievements |
This study was conducted to examine the effects of hypoxia and hypothermia on fat metabolism by focusing on UCP1 (Uncoupling protein 1), which is related to brown adipose tissue. We found that hypoxia might not influence the UCP1 expression, while it may inhibit the lipogenesis, thereby reducing the lipid storage in adipocytes.
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Report
(5 results)
Research Products
(18 results)
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[Presentation] Ambient Particular Matter (pm) Exposure Deteriorates Pulmonary Function in Early Childhood in Shanghai, China2015
Author(s)
Taguchi S, Otsuka M, Suzuki K, Yamasaki S, Kitagawa K, Yin X-J, Ji L, Zhou Y-R, Liu X, and Hashimoto T
Organizer
62th American College of Sport Medicine
Place of Presentation
San Diego, USA
Year and Date
2015-05-29
Related Report
Int'l Joint Research
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