| Project/Area Number |
25560383
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | National Center for Geriatrics and Gerontology |
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Principal Investigator |
NAKAI TOSHIHARU 国立研究開発法人国立長寿医療研究センター, 神経情報画像開発研究室, 室長 (30344170)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Ayuko 国立研究開発法人国立長寿医療研究センター, 神経情報画像開発研究室, 研究員 (50463203)
KUNIMI Mitsunobu 国立研究開発法人国立長寿医療研究センター, 神経情報画像開発研究室, 研究員 (70460384)
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| Co-Investigator(Renkei-kenkyūsha) |
KIYAMA Sachiko 国立研究開発法人国立長寿医療研究センター, 神経情報画像開発研究室, 研究員 (10612509)
SHIRAISHI Yoshiaki 神戸大学大学院工学研究科, 電気電子専攻・情報通信研究室, 准教授 (70351567)
KANAI Akira 豊橋創造大学, 理学療法学科, 教授 (60351201)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 認知訓練 / 加齢・老化 / 脳機能イメージング / 認知症 / 仮想作業 / 神経ネットワーク解析 / モーションキャプチャ / 運動制御 / 加齢 老化 |
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| Outline of Final Research Achievements |
A neuroimaging model of chopsticks manipulation using fMRI was designed in order to investigate its role as a cognitive motor training in daily life. The subjects performed virtual performance of bean transfer test which is employed as one of the physical activity batteries for older adults. By introducing precise reaction and execution time, the effect of aging was significantly observed at the switching timing between the manipulations. The success rate of operation correlated with the activation in the left parietal lobe. Among the resting state networks, activation in the default mode and sensory motor networks correlated with the performance of the subjects. It was suggested that fMRI may provide the biomarker to evaluate the response to cognitive motor intervention.
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