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Development of two apparatuses used in the optical measurement: oscillation free mechanical stimulator and transparent electrode for electrical stimulation

Research Project

Project/Area Number 25560434
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Brain biometrics
Research InstitutionShimane University

Principal Investigator

Hirota Akihiko  島根大学, 医学部, 教授 (50156717)

Co-Investigator(Kenkyū-buntansha) ITO Shin-ichi  島根大学, 医学部, 准教授 (10145295)
HAMA Noriyuki  島根大学, 医学部, 助教 (60422010)
KAWAI Minako  島根大学, 医学部, 助教 (50710109)
Co-Investigator(Renkei-kenkyūsha) YAMADA Yasuji  島根大学, 総合理工学部, 教授 (10362906)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords膜電位の光学測定 / 振動ノイズ / 機械刺激装置 / 無振動 / 透明電極 / 低抵抗透明導電体 / 電気刺激 / ノイズ / 光学測定
Outline of Final Research Achievements

We have developed two apparatuses. One is mechanical stimulator and the other is transparent electrode for electrical stimulation. These are commercially available for electrophysiological experiments, but neither of them can be applied to the experiment using optical technique. The problem of the former is physical oscillations it produces. By introducing a pair of neodymium magnets we succeeded in reducing the oscillations without spoiling high precision in the position. Concerning the latter, we had already developed a transparent electrode for electrical recording which can be used in the recording area during optical measurement. However, when applied to stimulation, the transparent conductive film made of Ga doped ZnO (GZO) is broken due to the heat caused by the stimulus current. We solved this problem by reducing the electrical resistance of the conductive part. The GZO film was covered with the film made of Nb doped TiO2 (NTO) (NTO), followed by annealing process.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (16 results)

All 2016 2015 2014 2013

All Journal Article (2 results) Presentation (14 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Optical imaging of the propagation patterns of neural responses in the rat sensory cortex: Comparison under two different anesthetic conditions2015

    • Author(s)
      Hama N, Ito S, Hirota A.
    • Journal Title

      Neuroscience

      Volume: 264 Pages: 126-133

    • DOI

      10.1016/j.neuroscience.2014.08.059

    • Related Report
      2014 Research-status Report
  • [Journal Article] Improvement of the optical imaging technique for intact rat brain using a plano-concave lens2014

    • Author(s)
      Kawai M, Hama N, Ito S, Hirota A.
    • Journal Title

      Journal of Physiological Sciences

      Volume: 64 Issue: 6 Pages: 445-449

    • DOI

      10.1007/s12576-014-0336-5

    • NAID

      40020259672

    • Related Report
      2014 Research-status Report
  • [Presentation] Acute changes in the propagating excitation wave pattern on the rat somatosensory cortex.2016

    • Author(s)
      Minako Kawai, Noriyuki Hama, Shin-ichi Ito, Akihiko Hirota
    • Organizer
      第93回 日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2016-03-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] ラットの尺骨神経挫滅後急性期における体性感覚野の興奮波伝播パターンの変化2015

    • Author(s)
      河合美菜子、濱徳行、伊藤眞一、廣田秋彦
    • Organizer
      第76回日本体力医学会中国・四国地方会
    • Place of Presentation
      高知大学(高知市)
    • Year and Date
      2015-11-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] ラットの尺骨神経挫滅後急性期における感覚野興奮波伝播パターンの変化2015

    • Author(s)
      河合美菜子、濱徳行、伊藤眞一、廣田秋彦
    • Organizer
      第67回 日本生理学会中国四国地方会
    • Place of Presentation
      米子コンベンションセンター(米子市)
    • Year and Date
      2015-10-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effects of excitation wave induced by forelimb stimulation on the propagation pattern of excitation wave induced by hindlimb stimulation in the rat sensorimotor cortex recorded with an optical recording system.2015

    • Author(s)
      Noriyuki Hama, Minako Kawai, Shin-Ichi Ito, Akihiko Hirota
    • Organizer
      The 45th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      McCormick Place in Chicago, IL USA
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Analysis of the effects of excitation wave induced by forelimb stimulation on the initiation time and the propagation pattern of excitation wave induced by hindlimb stimulation in the rat sensorimotor cortex recorded with an optical recording system.2015

    • Author(s)
      Noriyuki Hama, Minako Kawai, Shin-Ichi Ito, Akihiko Hirota
    • Organizer
      第38回日本神経科学学会
    • Place of Presentation
      神戸国際会議場展示場(神戸市)
    • Year and Date
      2015-07-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effects of forelimb stimulation on the propagating excitatory wave evoked by hindlimb2015

    • Author(s)
      Noriyuki Hama, Minako Kawai, Shin-ichi Ito, Akihiko Hirota
    • Organizer
      第92回 日本生理学会大会
    • Place of Presentation
      神戸国際会議場、神戸国際展示場(神戸市)
    • Year and Date
      2015-03-21 – 2015-03-23
    • Related Report
      2014 Research-status Report
  • [Presentation] ラット体性感覚野における前肢刺激の後肢刺激誘発興奮波に対する抑制効果2014

    • Author(s)
      濱 徳行,河合 美菜子,伊藤 眞一,廣田 秋彦
    • Organizer
      第66回日本生理学会中国四国地方会
    • Place of Presentation
      情報通信交流館 e-とぴあ・かがわ(高松市)
    • Year and Date
      2014-11-01 – 2014-11-02
    • Related Report
      2014 Research-status Report
  • [Presentation] 女子学生におけるエキセントリック収縮後の骨格筋サテライトセル活性化2014

    • Author(s)
      今岡 洋子、河合 美菜子、森 大志、宮田 浩文
    • Organizer
      第69回 日本体力医学会大会
    • Place of Presentation
      長崎大学文教キャンパス(長崎市)
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] Suppressive effect of forelimb stimulation on the spatio-temporal pattern of hindlimb stimulation-induced neural response in the rat somatosensory cortex2014

    • Author(s)
      Noriyuki Hama, Minako Kawai, Shin-ichi Ito, Akihiko Hirota
    • Organizer
      第37回日本神経科学学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Effect of forelimb stimulation on the hindlimb stimulation-induced propagating excitation in the rat sensorimotor cortex detected by optical recording system.2014

    • Author(s)
      濱 徳行、河合 美菜子、伊藤 眞一、廣田 秋彦
    • Organizer
      第91回 日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島市)
    • Related Report
      2013 Research-status Report
  • [Presentation] Effects of forelimb stimulation on the spatiotemporal pattern of neural response evoked by hindlimb stimulation in the rat sensorimotor cortex studied with multiple site optical recording system2013

    • Author(s)
      濱 徳行、伊藤 眞一、廣田 秋彦
    • Organizer
      第36回日本神経科学学会
    • Place of Presentation
      国立京都国際会館 (京都市)
    • Related Report
      2013 Research-status Report
  • [Presentation] Effects of anesthetics on the spatio-temporal pattern of neural activity in the rat sensory cortex detected by optical recording system.2013

    • Author(s)
      濱 徳行、伊藤 眞一、廣田 秋彦
    • Organizer
      日本動物学会大会第84回岡山大会
    • Place of Presentation
      岡山大学津島キャンパス(岡山市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 光学的膜電位測定法を用いたラット感覚運動野における後肢興奮波伝播パターンに対する前肢同時刺激の影響の解析2013

    • Author(s)
      河合美菜子,濱徳行,伊藤眞一,廣田秋彦
    • Organizer
      第65回日本生理学会中国四国地方会
    • Place of Presentation
      川崎医科大学現代医学教育博物館(岡山県倉敷市)
    • Related Report
      2013 Research-status Report
  • [Presentation] Comparison of the propagation patterns of neural activity in the rat sensorimotor cortex under different anesthetics detected with multiple site optical recording system.2013

    • Author(s)
      Hama N, Ito S, Hirota A
    • Organizer
      Society for Neuroscience 43rd Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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