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Regulation of brain-immune association by stimulation of vagal activity

Research Project

Project/Area Number 25590204
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Experimental psychology
Research InstitutionNagoya University

Principal Investigator

OHIRA Hideki  名古屋大学, 環境学研究科, 教授 (90221837)

Co-Investigator(Renkei-kenkyūsha) SAKAKIBARA Masato  愛知学院大学, 心身科学部, 教授 (10221996)
MATSUNAGA Masahiro  愛知医科大学, 医学部, 講師 (00533960)
Research Collaborator SUGIURA Yuko  愛知淑徳大学, 文学研究科
GIDRON Yori  Free University of Brussel, Department of Psychology, Professor
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords実験系心理学
Outline of Final Research Achievements

It has been shown that individuals with higher resting heart rate variability (HRV) have higher capacity of regulation over stress. This study examined a hypothesis that manipulation to enhance HRV might facilitate stress regulation capacity. Participants conducted the biofeedback training of respiration which can enhance HRV, and then conducted an acute stress task (mental arithmetic task with time pressure) where psychological and physiological stress reactivity was evaluated.
An experimental group who conducted two trials of 10 min. biofeedback training showed robust enhancement of power of low frequency component of HRV. Further, the experimental group showed reduction of stress reactivity in subjective rating of stress and an inflammatory cytokine, compared to a control group who did not conduct the biofeedback training. Thus it was certificated that enhancement of HRV was effective to facilitate stress regulation capacity.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2015 2013 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results) (of which Invited: 2 results)

  • [Journal Article] Vagal nerve activity as a moderator of brain–immune relationships.2013

    • Author(s)
      Ohira H, Matsunaga M, Osumi T, Fukuyama S, Shinoda J, Yamada J, Gidron Y.
    • Journal Title

      Journal of neuroimmunology.

      Volume: 260 Issue: 1-2 Pages: 28-36

    • DOI

      10.1016/j.jneuroim.2013.04.011

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 精神健康構造の包括理解2015

    • Author(s)
      大平 英樹
    • Organizer
      日本衛生学会
    • Place of Presentation
      和歌山県民文化会館
    • Year and Date
      2015-03-26
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] ストレスと認知機能:脳と身体の機能的相関‐ストレスよる意思決定の変容

    • Author(s)
      大平 英樹
    • Organizer
      日本ストレス学会
    • Place of Presentation
      徳島大学
    • Related Report
      2013 Research-status Report
    • Invited

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Published: 2014-07-25   Modified: 2019-07-29  

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