• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

SERS-DNA sequencer

Research Project

Project/Area Number 25600049
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Nanobioscience
Research InstitutionOsaka University (2013, 2015)
Waseda University (2014)

Principal Investigator

Yamaguchi Yoshinori  大阪大学, 工学(系)研究科(研究院), 教授 (20386634)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsDNAシーケンサ / 表面増強ラマン散乱 / マイクロチップ / 普及型DNAシーケンサ / ナノ剣山増強ラマンデバイス / ナノ剣山 / DNAシーケンサー / 普及型DNAシーケンサー
Outline of Final Research Achievements

In this study, as the first step for DNA sequencer based on surface enhanced Raman spectroscopy (SERS), we invented the SERS active substrate that enable to detect the surface enhanced Raman signal from single molecule. This result and invention of the SERS active nano-needle mountain is the big step for the SERS based DNA sequencer.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (14 results)

All 2016 2015 2014 Other

All Int'l Joint Research (2 results) Journal Article (12 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 12 results,  Acknowledgement Compliant: 7 results,  Open Access: 2 results)

  • [Int'l Joint Research] 華東理工大学/理学研究科(中国)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] 上海理工大学/光電信息研究院(中国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Capillary electrophoresis of RNA in hydroxyethylcellulose polymer with various molecular weights.2016

    • Author(s)
      Zhenqing Li, Chenchen Liu, Dawei Zhang, Yoshinori Yamaguchi
    • Journal Title

      Journal of Chromatography B

      Volume: 1011 Pages: 114-120

    • DOI

      10.1016/j.jchromb.2015.12.057

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Electrophoresis of Periodontal Pathogens in Poly (ethyleneoxide) Solutions with Uncoated Capillary2015

    • Author(s)
      Zhenqing Li, Ronglin Yang, Q Wang, Dawei Zhang, Songlin Zhuang, Yoshinori Yamaguchi
    • Journal Title

      Analytical Biochemistry

      Volume: 471 Pages: 70-72

    • DOI

      10.1016/j.ab.2014.11.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Polyethylene Oxide (PEO) and Polyethylene Glycol (PEG) Polymer Sieving Matrix for RNA Capillary Electrophoresis2015

    • Author(s)
      Yoshinori Yamaguchi, Zhenqing Li, Xifang Zhu, Chenchen Liu, Dawei Zhang, Xiaoming Dou
    • Journal Title

      PLoS One

      Volume: 10(6) Issue: 5 Pages: e0123406-e0123406

    • DOI

      10.1371/journal.pone.0123406

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Analysis of small interfering RNA by capillary electrophoresis in hydroxyethylcellulose solutions2015

    • Author(s)
      Chenchen Liu, Yoshinori Yamaguchi, Xifang Zhu, Zhenqing Li, Yi Ni, Xaoming Dou
    • Journal Title

      Electrophoresis

      Volume: 36 Issue: 14 Pages: 1651-1657

    • DOI

      10.1002/elps.201500018

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Time-lapse Raman imaging of osteoblast differentiation2015

    • Author(s)
      Aya Hashimoto, Yoshinori Yamaguchi, Liang-da Chiu, Chiaki Morimoto, Katsumasa Fujita, Masahide Takedachi, Satoshi Kawata, Shinya Murakami, Eiichi Tamiya
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 12529-12529

    • DOI

      10.1038/srep12529

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Activation energy of the Belousov– Zhabotinsky reaction in a gel with Fe(bpy)3 catalyst2014

    • Author(s)
      Yusuke Hara, Yoshinori Yamaguchi, Hiroyuki Mayama, Kenji Fujimoto
    • Journal Title

      Chemistry Letters

      Volume: 43 Pages: 673-675

    • NAID

      130004868109

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Quantification of Periodontal Pathogens Cell Counts by Capillary Electrophoresis2014

    • Author(s)
      Zhenqing Li, Shaoxiong Chen, Chenchen Liu, Dawei Zhang, Xiaoming Dou, Yoshinori Yamaguchi
    • Journal Title

      Journal of Chromatography A

      Volume: 1361 Pages: 286-290

    • DOI

      10.1016/j.chroma.2014.07.100

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Determination and quantification of Escherichia coli by capillary electrophoresis2014

    • Author(s)
      Zhenqing Li, De Li, Dawei Zhang, Yoshinori Yamaguchi
    • Journal Title

      Analyst

      Volume: 139 Issue: 23 Pages: 6113-6117

    • DOI

      10.1039/c4an01649a

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Electromigration behavior of nucleic acids in capillary electrophoresis under pulsed-field conditions2014

    • Author(s)
      Zhenqing Li, Chenchen Liu, Xiaoming Dou, Yi Ni, Jiaxuan Wang, Yoshinori Yamaguchi
    • Journal Title

      Journal of Chromatography A

      Volume: 1331 Pages: 100-107

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Capillary electrophoresis of wide range DNA fragments in mixed solution of hydroxyethyl cellulose2014

    • Author(s)
      Zhenqing Li, Chenchen Liu, Yoshinori Yamaguchi, Yi Ni, Qingxiang You, Xiaoming Dou
    • Journal Title

      Analytical Methods

      Volume: 6 Issue: 8 Pages: 2473-2477

    • DOI

      10.1039/c3ay41965g

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] In situ Raman imaging of osteoblastic mineralization2014

    • Author(s)
      Aya Hashimoto, Liang-da Chiu, Keigo Sawada, Katsumasa Fujita, Masahide Takedachi, Yoshinori Yamaguchi, Satoshi Kawata, Shinya Murakami, Eiichi Tamiya
    • Journal Title

      Journal of Raman Spectroscopy

      Volume: 45 Issue: 2 Pages: 157-161

    • DOI

      10.1002/jrs.4438

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Switching the Belousov-Zhabotinsky reaction with a Strong-Acid-Free Gel2014

    • Author(s)
      Y. Hara, Y. Yamaguchi, H. Mayama
    • Journal Title

      J. Phys. Chem. B

      Volume: 118 Issue: 2 Pages: 634-638

    • DOI

      10.1021/jp410915p

    • Related Report
      2013 Research-status Report
    • Peer Reviewed

URL: 

Published: 2014-07-25   Modified: 2022-01-31  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi