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Super resolution of soft X-ray microscope by structured light

Research Project

Project/Area Number 25600136
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Quantum beam science
Research InstitutionTohoku University

Principal Investigator

EJIMA Takeo  東北大学, 多元物質科学研究所, 准教授 (80261478)

Co-Investigator(Kenkyū-buntansha) YANAGIHARA Mihiro  東北大学, 多元物質科学研究所, 教授 (40174552)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords軟X線顕微鏡 / 多層膜光学系 / 構造化照明 / 超解像
Outline of Final Research Achievements

For super resolution of microscope in soft X-ray region, it was developped that a grazing incidence condeser to illuminate a sample by a structured light and a 5 axes manipulator to obtain phase information of the light passed through a sample. The grazing incidence condenser is developed for strucutred illumination with the use of a point light source. The condenser is composed of toroidal mirrors and the mirror was fabricated and evaluated. A reflection multilayer was deposited on the mirror surface and measured reflectance of the mirror is higher than 0.32 at 4.5 nm wavelength. The 5 axes manipulator was designed and fabricated to obtain phase information of the light, and the average displacement evaluated in x/y/z directions was 25nm/pulse and 2x10^{-6} rad/pulse in θx/θy rotational directions. With the use of these instruments, soft X-ray images of mouse liver-cell stained by Hematoxylin were taken.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (23 results)

All 2015 2014 2013 Other

All Journal Article (8 results) (of which Peer Reviewed: 7 results,  Acknowledgement Compliant: 1 results) Presentation (15 results) (of which Invited: 2 results)

  • [Journal Article] Efficient extreme ultraviolet emission from multiple laser-produced one-dimensional spherical plasmas2014

    • Author(s)
      Kensuke Yoshida, Shinsuke Fujioka, Takeshi Higashiguchi, et al.
    • Journal Title

      Applied Physics Express

      Volume: 7 Issue: 8 Pages: 086202-086202

    • DOI

      10.7567/apex.7.086202

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Multilayer coated grazing incidence condenser for large numerical aperture objective at wavelength of 4.5 nm2014

    • Author(s)
      T. Ejima, T. Hatano, K. Ohno, T. Fukayama, S. Aihara, M. Yanagihara, and T. Tsuru
    • Journal Title

      Applied Optics

      Volume: 53 Pages: 6846-6852

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design and performance of a new VIS-VUV photoluminescence beamline at UVSOR-III2014

    • Author(s)
      K. Fukui, R. Ikematsu, Y. Imoto, M. Kitaura, K. Nakagawa, T. Ejima, E. Nakamura, M. Sakai, M. Hasumoto, and S. Kimura
    • Journal Title

      J. Synchrotron Rad.

      Volume: 21 Issue: 2 Pages: 452-455

    • DOI

      10.1107/s1600577513032931

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 「水の窓」波長域の軟X線顕微鏡による生物細胞観測2014

    • Author(s)
      江島丈雄、加道雅孝
    • Journal Title

      O plus E

      Volume: 36(3) Pages: 296-230

    • Related Report
      2013 Research-status Report
  • [Journal Article] Development of Soft X-ray Contact-type Microscope and Application to Micro-spectroscopy in Water-window2013

    • Author(s)
      T. Ejima, Y. Neichi, F. Ishida, and M. Yanagihara
    • Journal Title

      J. Phys.: Conf. Series

      Volume: 463 Pages: 12055-12055

    • DOI

      10.1088/1742-6596/463/1/012055

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] hemical Shift Images of Organelles in Leydig cells of Mice Testes2013

    • Author(s)
      T. Ejima, Y. Neichi, M. Yanagihara, M. Kado, M. Ishino, K. Yasuda, and S. Tamotsu
    • Journal Title

      J. Phys.: Conf. Series

      Volume: 463 Pages: 12047-12047

    • DOI

      10.1088/1742-6596/463/1/012047

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] nvestigation of sample preparation methods for EUV imaging of fixed bio-cells2013

    • Author(s)
      T. Ejima, F. Ishida, Y. Neichi, M. Yanagihara
    • Journal Title

      J. Phys.: Conf. Series

      Volume: 425 Issue: 18 Pages: 182007-182007

    • DOI

      10.1088/1742-6596/425/18/182007

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] evelopment of soft X-ray contact microscope for in-situ identification of organelles2013

    • Author(s)
      T. Ejima, Y. Neichi, F. Ishida, M. Yanagihara
    • Journal Title

      J. Phys.: Conf. Series

      Volume: 425 Issue: 18 Pages: 182008-182008

    • DOI

      10.1088/1742-6596/425/18/182008

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 炭素の窓用多層膜トロイダルミラーの反射率計測2015

    • Author(s)
      羽多野忠,大野広大,相原翔学,江島丈雄
    • Organizer
      第28回日本放射光学会年会
    • Place of Presentation
      立命館大学草津キャンパス
    • Year and Date
      2015-01-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 水の窓における生物細胞内構造のコントラスト2015

    • Author(s)
      江島丈雄,加道雅孝,石野雅彦,青山雅人,安田恵子,保智己
    • Organizer
      第28回日本放射光学会年会
    • Place of Presentation
      立命館大学草津キャンパス
    • Year and Date
      2015-01-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 軟X線相関顕微法による生物細胞内の形態と化学組成2014

    • Author(s)
      江島丈雄
    • Organizer
      東北大学金属材料研究所共同利用ワークショップ
    • Place of Presentation
      東北大学金属材料研究所
    • Year and Date
      2014-12-15
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 軟X線相関顕微法とその生物観察応用2014

    • Author(s)
      江島丈雄
    • Organizer
      第4回宇都宮大学オプトバイオシンポジウム
    • Place of Presentation
      宇都宮大学
    • Year and Date
      2014-12-11
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 培養液中のライディッヒ細胞の軟Ⅹ線吸収分光測定2014

    • Author(s)
      江島丈雄、加道雅孝、石野雅彦、青山雅人、安田恵子、保智己
    • Organizer
      UVSORシンポジウム2014
    • Place of Presentation
      分子科学研究所
    • Year and Date
      2014-11-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] XAS Spectra of a Leydig Cell in Cultural Fluid to Evaluate Contrast of Organelles in Water Window2014

    • Author(s)
      T. Ejima, R. Hirose, M. Ishino, M. Kado, M. Aoyama, K. Yasuda, and S. Tamotsu
    • Organizer
      The 12th international conference on x-ray microscopy
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-10-26 – 2014-10-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] N-K吸収端近傍における生物細胞内構造のコントラスト2014

    • Author(s)
      江島丈雄、廣瀬遼一、加道雅孝、石野雅彦、青山雅人、安田恵子、保智己
    • Organizer
      第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] アポトーシス細胞における赤外吸収スペクトル2014

    • Author(s)
      江島丈雄
    • Organizer
      『軟X線による細胞内形態解析』研究会
    • Place of Presentation
      宮城蔵王ロイヤルホテル
    • Year and Date
      2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] マウス精巣ライディッヒ細胞の顕微分光測定2014

    • Author(s)
      廣瀬僚一,江島丈雄,柳原美廣,加道雅孝,石野雅彦,安田恵子,青山雅人,保智己
    • Organizer
      第27回日本放射光学会年会
    • Place of Presentation
      広島国際会議場
    • Related Report
      2013 Research-status Report
  • [Presentation] Development of a grazing-incidence condenser for large NA objective2013

    • Author(s)
      T. Ejima, T. Hatano, K. Ohno, T. Fukayama, S. Aihara, & M. Yanagihara
    • Organizer
      The 12th Symposium on X-ray Imaging Optics
    • Place of Presentation
      大阪
    • Related Report
      2013 Research-status Report
  • [Presentation] Development of a grazing-incidence condenser for SX microscope2013

    • Author(s)
      T. Ejima, T. Hatano, K. Ohno, T. Fukayama, S. Aihara, & M. Yanagihara
    • Organizer
      the 38th International conference on Vacuum Ultraviolet and X-ray Physics
    • Place of Presentation
      Hefei, China
    • Related Report
      2013 Research-status Report
  • [Presentation] 点光源軟X線顕微鏡の集光光学系の開発

    • Author(s)
      江島丈雄、羽多野忠、大野広大、深山宇広、相原翔学、柳原美廣
    • Organizer
      レーザー学会第450回研究会
    • Place of Presentation
      早稲田大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 波長4.5nm用軟X線顕微鏡の斜入射照明光学系の開発

    • Author(s)
      江島丈雄,羽多野忠,大野広大,深山宇大,相原翔学,柳原美廣
    • Organizer
      第74回応用物理学会秋季学術講演会
    • Place of Presentation
      同志社大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 球対称BEUV放射プラズマの電子密度計測

    • Author(s)
      鵜篭照之,吉田健祐,錦野将元,藤岡慎介,西村博明,東口武史,江島丈雄,富田健太郎,鈴木千尋,大橋隼人,田中のぞみ,疇地宏,鈴木悠平,川崎将人,廣瀬僚一
    • Organizer
      第74回応用物理学会秋季学術講演会
    • Place of Presentation
      同志社大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 球対称ガドリニウムプラズマからのB-EUV放射特性とスペクトル特性

    • Author(s)
      吉田健祐,錦野将元,大橋隼人,鈴木千尋,廣瀬僚一,江島丈雄,富田健太郎,東口武史,川崎将人,鈴木悠平,藤岡慎介,鵜篭照之,田中のぞみ,西村博明,疇宏
    • Organizer
      第74回応用物理学会秋季学術講演会
    • Place of Presentation
      同志社大学
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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