| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Addition of a diboron reagent into aromatic compounds containing two nitrogen atoms, that is 4,4’-bipyridines, took place efficiently at 60-110 °C under transition-metal-free conditions to give dearomatized compounds in good yields. The boryl group on the dearomatized compounds might be transferred to unsaturated organic molecules, such as pyrazines and alkynes, under mild conditions (room temperature ~ 60 °C). Based on these two elementary reactions, 4,4’-bipyridine-catalyzed diboration of pyrazines and alkynes was established. The insights obtained by this research would be useful for development of molecular transformations based on dearomatization.
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