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Creation of new time measurement-chemiluminescent reaction and prototyping of compact analyzer

Research Project

Project/Area Number 25620103
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Analytical chemistry
Research InstitutionIbaraki University

Principal Investigator

IGARASHI Shukuro  茨城大学, 工学部, 教授 (70150258)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords時間計測 / 化学発光 / 時計反応 / 自己触媒反応 / iTem-CL / 微量分析 / 簡易分析 / 極限計測
Outline of Final Research Achievements

In chlorophyll chemiluminescence system, a specific inductive time delay phenomenon of saccharide maltose was found, and the time measurement - chemiluminescence analysis (iTem-CL method) of 0.1μM maltose was established. Moreover, by the kinetic analysis of reaction mechanism for autocatalytic reactions, it was proved that iTem-CL method is a constant sensitivity or "infinite sensitivity" method. For the prototype of compact analyzer, when using the existing chemiluminescence analyzer (Gene Light S-200 made in Microtec Nition ), that even without the improvement of the hard aspect of the apparatus body is available was found. As a basis, the detailed examination of factors such as temperature, mixture, the signal detection was performed. The iTem-CL method was a simple and easy analytical method for clinical sample (maltose in an intravenous feeding agent) and the environmental sample (Ru(III) ion of river water), and extensive application is expected in future.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2014 2013

All Presentation (2 results)

  • [Presentation] 自己触媒反応を用いる時間計測―化学発光法 -微量Ru(III)の分析-2014

    • Author(s)
      平野 恭介、石橋 真奈美、遠藤 大介、加藤 潤、山口 仁志、五十嵐 淑郎
    • Organizer
      第25回日本化学会関東支部茨城地区研究交流会
    • Place of Presentation
      ワークプラザ勝田(茨城県ひたちなか市)
    • Year and Date
      2014-10-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] クロロフィル化学発光を用いる反応遅延成分(糖類)の時間計測-化学発光分析法の開発2013

    • Author(s)
      遠藤大介,大友孝郎,五十嵐淑郎
    • Organizer
      第24回日本化学会関東支部茨城地区研究交流会
    • Place of Presentation
      茨城県ひたちなか市大字東石川1279 ワークプラザ勝田
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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